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hPL-IN-2

Name: hPL-IN-2
Brand: TargetMol
SKU: T77679
Price: 44 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T77679Cas No. 24900-61-6

hPL-IN-2 is a potent, reversible and non-competitive inhibitor of Pancreatic lipase (IC50: 1.63 μM) that can be used to investigate obesity-related diseases.

hPL-IN-2

🥰Excellent

Purity: 98.75%

Catalog No. T77679Cas No. 24900-61-6

hPL-IN-2 is a potent, reversible and non-competitive inhibitor of Pancreatic lipase (IC50: 1.63 μM) that can be used to investigate obesity-related diseases.

Pack Size	Price	Availability
5 mg	$44	In Stock
10 mg	$74	In Stock
25 mg	$125	In Stock
50 mg	$183	In Stock
100 mg	$267	In Stock
200 mg	$375	In Stock

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Batch Information

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Purity:98.75%

Resource Download

COA HPLC HNMR

Product Introduction

Bioactivity

Description	hPL-IN-2 is a potent, reversible and non-competitive inhibitor of Pancreatic lipase (IC50: 1.63 μM) that can be used to investigate obesity-related diseases.
Targets&IC50	PL (human):1.7 μM, Pancreatic lipase:1.63 μM

Chemical Properties

Molecular Weight	443.11
Formula	C₁₉H₁₁Cl₄NO₃
Cas No.	24900-61-6
Smiles	O=C(NC1=CC=C(OC2=CC=C(Cl)C=C2)C(Cl)=C1)C=3C=C(Cl)C=C(Cl)C3O
Relative Density.	no data available

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 55 mg/mL (124.12 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.2568 mL	11.2839 mL	22.5678 mL	112.8388 mL
5 mM	0.4514 mL	2.2568 mL	4.5136 mL	22.5678 mL
10 mM	0.2257 mL	1.1284 mL	2.2568 mL	11.2839 mL
20 mM	0.1128 mL	0.5642 mL	1.1284 mL	5.6419 mL
50 mM	0.0451 mL	0.2257 mL	0.4514 mL	2.2568 mL
100 mM	0.0226 mL	0.1128 mL	0.2257 mL	1.1284 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

pancreatic lipasehPL-IN-2hPLIN2