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Anti-Phospho-eNOS (Ser1177) Polyclonal Antibody (Synonyms: p-eNOS (Ser1177), p-eNOS (S1177), NOSIII, NOS3, N...)
Catalog No. TMAB-01405 Copy Product Info
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Anti-Phospho-eNOS (Ser1177) Polyclonal Antibody is a Rabbit antibody targeting Phospho-eNOS (Ser1177). Anti-Phospho-eNOS (Ser1177) Polyclonal Antibody can be used in WB.
Anti-Phospho-eNOS (Ser1177) Polyclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAB-01405
Synonyms p-eNOS (Ser1177), p-eNOS (S1177), NOSIII, NOS3, NOS type III, NOS III, NOS 3, nitric oxide synthase, endothelial, Nitric oxide synthase endothelial, Nitric oxide synthase 3(endothelial cell), Nitric oxide synthase 3 endothelial cell, Nitric oxide synthase 3, eNOS (p-Ser1177), eNOS (p-S1177), Endothelial NOS, Endothelial nitric oxide synthase 3, Endothelial nitric oxidase synthase, ecNOS, EC NOS, Constitutive NOS, cNOS
Anti-Phospho-eNOS (Ser1177) Polyclonal Antibody is a Rabbit antibody targeting Phospho-eNOS (Ser1177). Anti-Phospho-eNOS (Ser1177) Polyclonal Antibody can be used in WB.
Anti-Phospho-eNOS
(Ser1177) Polyclonal Antibody
(Ser1177) Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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| Description | Anti-Phospho-eNOS (Ser1177) Polyclonal Antibody is a Rabbit antibody targeting Phospho-eNOS (Ser1177). Anti-Phospho-eNOS (Ser1177) Polyclonal Antibody can be used in WB. |
| Synonyms | p-eNOS (Ser1177), p-eNOS (S1177), NOSIII, NOS3, NOS type III, NOS III, NOS 3, nitric oxide synthase, endothelial, Nitric oxide synthase endothelial, Nitric oxide synthase 3(endothelial cell), Nitric oxide synthase 3 endothelial cell, Nitric oxide synthase 3, eNOS (p-Ser1177), eNOS (p-S1177), Endothelial NOS, Endothelial nitric oxide synthase 3, Endothelial nitric oxidase synthase, ecNOS, EC NOS, Constitutive NOS, cNOS |
| Ig Type | IgG |
| Reactivity | Human (predicted:Mouse,Rat) |
| Verified Activity | Sample: Lane 1: Human HUVEC cell lysates Lane 2: Human HUVEC treated with 100 µM Pervanadate (PV) for 10 minutes Primary: Anti-Phospho-eNOS (Ser1177) (TMAB-01405) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 133 kDa Observed band size: 135 kDa  |
| Application | |
| Recommended Dose | WB: 1:500-1000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cell membrane. Membrane, caveola. Cytoplasm, cytoskeleton. Golgi apparatus. Note=Specifically associates with actin cytoskeleton in the G2 phase of the cell cycle; which is favored by interaction with NOSIP and results in a reduced enzymatic activity. |
| Tissue Specificity | Platelets, placenta, liver and kidney. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | Nitric oxide synthase NOS oxidizes a guanidine nitrogen of arginine releasing nitric oxide in the form of a free radical and citrulline. Nitric oxide thus generated acts as a messenger in diverse functions including vasodilation neurotransmission, anti tumor and anti pathogenic activities. NOS is classified under three types: neuronal NOS (nNOS) or brain NOS (bNOS); inducible NOS (iNOS) or macrophage NOS (mNOS); and endothelial NOS (eNOS). |
| Immunogen | KLH conjugated Synthesised phosphopeptide: mouse eNOS around the phosphorylation site of Ser1177 |
| Antigen Species | Mouse |
| Gene Name | NOS3 |
| Gene ID | |
| Protein Name | Nitric oxide synthase, endothelial |
| Uniprot ID | |
| Biology Area | Response to hypoxia,Platelets,Nitric oxide associated,Oxidative Stress,Hypoxia,Oxidative stress,NOS |
| Function | Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. NO mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets. Isoform eNOS13C: Lacks eNOS activity, dominant-negative form that may down-regulate eNOS activity by forming heterodimers with isoform 1. |
| Molecular Weight | Theoretical: 133 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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