Anti-Phospho-eNOS (Ser1177) Polyclonal Antibody

Name: Anti-Phospho-eNOS (Ser1177) Polyclonal Antibody
Brand: TargetMol
SKU: TMAB-01405
Rating: 4.5 (1 reviews)

(Synonyms: p-eNOS (Ser1177), p-eNOS (S1177), NOSIII, NOS3, NOS type III, NOS III, NOS 3, nitric oxide synthase, endothelial, Nitric oxide synthase endothelial, Nitric oxide synthase 3(endothelial cell), Nitric oxide synthase 3 endothelial cell, Nitric oxide synthase 3, eNOS (p-Ser1177), eNOS (p-S1177), Endothelial NOS, Endothelial nitric oxide synthase 3, Endothelial nitric oxidase synthase, ecNOS, EC NOS, Constitutive NOS, cNOS) Copy Product Info

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Synonyms: p-eNOS (Ser1177), p-eNOS (S1177), NOSIII, NOS3, NOS type III, NOS III, NOS 3, nitric oxide synthase, endothelial, Nitric oxide synthase endothelial, Nitric oxide synthase 3(endothelial cell), Nitric oxide synthase 3 endothelial cell, Nitric oxide synthase 3, eNOS (p-Ser1177), eNOS (p-S1177), Endothelial NOS, Endothelial nitric oxide synthase 3, Endothelial nitric oxidase synthase, ecNOS, EC NOS, Constitutive NOS, cNOS

Catalog No. TMAB-01405 Copy Product Info

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Anti-Phospho-eNOS (Ser1177) Polyclonal Antibody is a Rabbit antibody targeting Phospho-eNOS (Ser1177). Anti-Phospho-eNOS (Ser1177) Polyclonal Antibody can be used in WB.

Anti-Phospho-eNOS
(Ser1177) Polyclonal Antibody

Pack Size	Price	USA Stock	Global Stock
50 μL	$220	7-10 days	7-10 days
100 μL	$372	7-10 days	7-10 days
200 μL	$529	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Bioactivity

Description	Anti-Phospho-eNOS (Ser1177) Polyclonal Antibody is a Rabbit antibody targeting Phospho-eNOS (Ser1177). Anti-Phospho-eNOS (Ser1177) Polyclonal Antibody can be used in WB.
Synonyms	p-eNOS (Ser1177), p-eNOS (S1177), NOSIII, NOS3, NOS type III, NOS III, NOS 3, nitric oxide synthase, endothelial, Nitric oxide synthase endothelial, Nitric oxide synthase 3(endothelial cell), Nitric oxide synthase 3 endothelial cell, Nitric oxide synthase 3, eNOS (p-Ser1177), eNOS (p-S1177), Endothelial NOS, Endothelial nitric oxide synthase 3, Endothelial nitric oxidase synthase, ecNOS, EC NOS, Constitutive NOS, cNOS
Ig Type	IgG
Reactivity	Human (predicted:Mouse,Rat)

Application	WB
Recommended Dose	WB: 1:500-1000
Antibody Type	Polyclonal
Host Species	Rabbit
Subcellular Localization	Cell membrane. Membrane, caveola. Cytoplasm, cytoskeleton. Golgi apparatus. Note=Specifically associates with actin cytoskeleton in the G2 phase of the cell cycle; which is favored by interaction with NOSIP and results in a reduced enzymatic activity.
Tissue Specificity	Platelets, placenta, liver and kidney.
Construction	Polyclonal Antibody
Purification	Protein A purified
Appearance	Liquid
Formulation	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration	1 mg/mL
Research Background	Nitric oxide synthase NOS oxidizes a guanidine nitrogen of arginine releasing nitric oxide in the form of a free radical and citrulline. Nitric oxide thus generated acts as a messenger in diverse functions including vasodilation neurotransmission, anti tumor and anti pathogenic activities. NOS is classified under three types: neuronal NOS (nNOS) or brain NOS (bNOS); inducible NOS (iNOS) or macrophage NOS (mNOS); and endothelial NOS (eNOS).

Antigen Details

Immunogen	KLH conjugated Synthesised phosphopeptide: mouse eNOS around the phosphorylation site of Ser1177
Antigen Species	Mouse
Gene Name	NOS3
Gene ID	18127
Protein Name	Nitric oxide synthase, endothelial
Uniprot ID	P70313
Biology Area	Response to hypoxia,Platelets,Nitric oxide associated,Oxidative Stress,Hypoxia,Oxidative stress,NOS
Function	Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. NO mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets. Isoform eNOS13C: Lacks eNOS activity, dominant-negative form that may down-regulate eNOS activity by forming heterodimers with isoform 1.