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Anti-MBP Antibody (8X293)

😃Good
Catalog No. TMAC-02715

Anti-MBP Antibody (8X293) is a Rabbit antibody targeting MBP. Anti-MBP Antibody (8X293) can be used in WB,IHC.

Anti-MBP Antibody (8X293)

Anti-MBP Antibody (8X293)

😃Good
Catalog No. TMAC-02715
Anti-MBP Antibody (8X293) is a Rabbit antibody targeting MBP. Anti-MBP Antibody (8X293) can be used in WB,IHC.
Pack SizePriceAvailabilityQuantity
50 μL$2987-10 days
100 μL$4967-10 days
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Product Introduction

Bioactivity
Description
Anti-MBP Antibody (8X293) is a Rabbit antibody targeting MBP. Anti-MBP Antibody (8X293) can be used in WB,IHC.
Ig Type
IgG
Reactivity
Human
Application
Recommended Dose
WB: 1:1000; IHC: 1:50-200
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundMyelin basic protein (MBP) is the major extrinsic membrane protein of central nervous system myelin. MBP phosphorylation at Threonine 125 is a complex regulatory process that modulates the contribution of MBP to the stability of the myelin sheath. Mitogen-activated protein kinases modulate MBP phosphorylation during myelinogenesis and in the demyelinating disease multiple sclerosis. MBP phosphorylation is regulated by high-frequency stimulation but not low-frequency stimulation of the alveus, the myelinated output fibers of the hippocampus. It is proposed that during periods of increased neuronal activity, calcium activates axonal nitric oxide synthase, which generates the intercellular messengers nitric oxide and superoxide and regulates the phosphorylation state of MBP by MAPK.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 33/21/19 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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