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Anti-MBP Antibody (8X293)
😃Good
Catalog No. TMAC-02715
Alias Shi, Myelin basic protein, Myelin A1 protein, Mbp, MBP
Anti-MBP Antibody (8X293) is a Rabbit antibody targeting MBP. Anti-MBP Antibody (8X293) can be used in WB,IHC.
Anti-MBP Antibody (8X293)
Anti-MBP Antibody (8X293)
😃Good
Catalog No. TMAC-02715Alias Shi, Myelin basic protein, Myelin A1 protein, Mbp, MBP
Anti-MBP Antibody (8X293) is a Rabbit antibody targeting MBP. Anti-MBP Antibody (8X293) can be used in WB,IHC.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $298 | 7-10 days | |
| 100 μL | $496 | 7-10 days |
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Chemical Properties
| Description | Anti-MBP Antibody (8X293) is a Rabbit antibody targeting MBP. Anti-MBP Antibody (8X293) can be used in WB,IHC. |
| Synonyms | Shi, Myelin basic protein, Myelin A1 protein, Mbp, MBP |
| Ig Type | IgG |
| Clone | 8X293 |
| Reactivity | Human |
| Verified Activity | 1. Immunohistochemical analysis of paraffin-embedded rat brain tissue using anti-Myelin Basic Protein antibody. Counter stained with hematoxylin. 2. Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-Myelin Basic Protein antibody. Counter stained with hematoxylin. |
| Application | |
| Recommended Dose | WB: 1:1000; IHC: 1:50-200 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | Myelin basic protein (MBP) is the major extrinsic membrane protein of central nervous system myelin. MBP phosphorylation at Threonine 125 is a complex regulatory process that modulates the contribution of MBP to the stability of the myelin sheath. Mitogen-activated protein kinases modulate MBP phosphorylation during myelinogenesis and in the demyelinating disease multiple sclerosis. MBP phosphorylation is regulated by high-frequency stimulation but not low-frequency stimulation of the alveus, the myelinated output fibers of the hippocampus. It is proposed that during periods of increased neuronal activity, calcium activates axonal nitric oxide synthase, which generates the intercellular messengers nitric oxide and superoxide and regulates the phosphorylation state of MBP by MAPK. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 33/21/19 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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