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Anti-CD160 Antibody-APC (3P845) is a APC-conjugated Rabbit antibody targeting CD160. Anti-CD160 Antibody-APC (3P845) can be used in FCM.
Description | Anti-CD160 Antibody-APC (3P845) is a APC-conjugated Rabbit antibody targeting CD160. Anti-CD160 Antibody-APC (3P845) can be used in FCM. |
Ig Type | Monoclonal Rabbit IgG |
Clone | 3P845 |
Reactivity | Human |
Verified Activity | Flow cytometric analysis of Human CD160 expression on human whole blood lymphocytes. Cells were stained with APC-conjugated anti-Human CD160. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable lymphocytes. |
Application | FCM |
Recommended Dose | 10 μl/Test, 0.1 mg/ml |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human CD160 (rh CD160; TMPY-01905; NP_008984.1; Met1-Leu158) and conjugated with APC under optimum conditions, the unreacted APC was removed. |
Purification | Protein A |
Appearance | Liquid |
Formulation | PBS solution containing 0.5% BSA and 0.1% sodium azide |
Research Background | CD16 antigen, also known as Natural killer cell receptor BY55 and CD16, is a cell membrane protein which contains one Ig-like V-type (immunoglobulin-like) domain. CD16 is a GPI-anchored lymphocyte surface receptor in which expression is mostly restricted to the highly cytotoxic CD56(dim)CD16(+) peripheral blood NK subset. CD16 is a receptor showing broad specificity for both classical and non-classical MHC class I molecules. CD16 is expressed in spleen, peripheral blood, and small intestine. Expression of CD16 is restricted to functional NK and T cytotoxic lymphocytes. CD16 acts as a co-activator receptor for CD3-induced proliferation of CD4+ CD16+ T cells isolated from inflammatory skin lesions. Unique CD4+ CD16+ lymphocyte subset may play a role in the pathogenesis of skin inflammation. Activated NK lymphocytes release a soluble form of CD16 that functionally impairs the MHC-I-specific cytotoxic CD8(+) T lymphocyte responsiveness.Cancer ImmunotherapyCo-inhibitory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Detection: AntibodiesImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint Detection: FCM AntibodiesImmune Checkpoint Detection: IHC AntibodiesImmune Checkpoint TargetsImmunotherapyTargeted Therapy |
Conjucates | APC |
Others Formats | Unconjugated/PE |
Antibody Types Available | 3 |
Immunogen | Recombinant Human CD160 Protein (TMPY-01905) |
Antigen Species | Human |
Biology Area | Cancer Drug Targets |
Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
Transport | Shipping with blue ice. |
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