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Anti-Transferrin Receptor/TFRC Antibody (4F227)
(Synonyms: TR, TFRC, TfR1, TFR, T9, sTfR, p90, CD71) Copy Product Info
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Synonyms: TR, TFRC, TfR1, TFR, T9, sTfR, p90, CD71
Catalog No. TMAB-01889 Copy Product Info
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Anti-Transferrin Receptor/TFRC Antibody (4F227) is a Rabbit antibody targeting Transferrin Receptor/TFRC. Anti-Transferrin Receptor/TFRC Antibody (4F227) can be used in FCM,ICC/IF,WB.
Anti-Transferrin Receptor/TFRC Antibody
(4F227)
(4F227)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 25 μL | $154 | 7-10 days | 7-10 days | |
| 50 μL | $272 | 7-10 days | 7-10 days | |
| 100 μL | $488 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-Transferrin Receptor/TFRC Antibody (4F227) is a Rabbit antibody targeting Transferrin Receptor/TFRC. Anti-Transferrin Receptor/TFRC Antibody (4F227) can be used in FCM,ICC/IF,WB. |
| Synonyms | TR, TFRC, TfR1, TFR, T9, sTfR, p90, CD71 |
| Ig Type | IgG |
| Clone | 4F227 |
| Reactivity | Human,Rat (predicted:Mouse) |
| Application | |
| Recommended Dose | WB: 1:500-2000; ICC/IF: 1:50-200; FCM: 1μg/Test |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cell membrane; Single-pass type II membrane protein. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | This gene encodes a cell surface receptor necessary for cellular iron uptake by the process of receptor-mediated endocytosis. This receptor is required for erythropoiesis and neurologic development. Multiple alternatively spliced variants have been identified. [provided by RefSeq, Sep 2015] |
| Immunogen | A synthesized peptide: human Transferrin receptor |
| Antigen Species | Human |
| Gene Name | TFRC |
| Gene ID | |
| Protein Name | Transferrin receptor protein 1 |
| Uniprot ID | |
| Biology Area | Response to hypoxia,Serum Proteins,Non-lineage,Hypoxia,B Lymphocytic Lineage,T Lymphocytic Lineage,Erythrocytic Lineage,Surface Molecules |
| Function | Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system. A second ligand, the heditary hemochromatosis protein HFE, competes for binding with transferring for an overlapping C-terminal binding site. |
| Molecular Weight | Theoretical: 85 kDa. Actual: 90 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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