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[Sar9] Substance P acetate(77128-75-7 free base)

🥰Excellent
Catalog No. TP1862L

[Sar9]-Substance P acetate is one of NK-1 receptor agonist. The action of SP on progesterone metabolism was mimicked by the rNK1-specific agonist [Sar-9,Met(O2)11]-SP.

[Sar9] Substance P acetate(77128-75-7 free base)
Other Forms of [Sar9] Substance P acetate(77128-75-7 free base):
[Sar9] Substance PTP186277128-75-7
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[Sar9] Substance P acetate(77128-75-7 free base)

🥰Excellent
Purity: 96.67%
Catalog No. TP1862L
[Sar9]-Substance P acetate is one of NK-1 receptor agonist. The action of SP on progesterone metabolism was mimicked by the rNK1-specific agonist [Sar-9,Met(O2)11]-SP.
Pack SizePriceAvailabilityQuantity
1 mg$90In Stock
5 mg$182In Stock
10 mg$273In Stock
25 mg$493In Stock
50 mg$718In Stock
100 mg$987In Stock
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Batch Information

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Purity:96.67%
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COA MS HPLC

Product Introduction

Bioactivity
Description
[Sar9]-Substance P acetate is one of NK-1 receptor agonist. The action of SP on progesterone metabolism was mimicked by the rNK1-specific agonist [Sar-9,Met(O2)11]-SP.
Chemical Properties
Molecular Weight1421.71
FormulaC66H104N18O15S
SmilesO=C([C@H]1N(CCC1)C([C@@H](N)CCCNC(N)=N)=O)N[C@@H](CCCCN)C(N2[C@@H](CCC2)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCC(N)=O)C(N[C@H](C(N[C@H](C(N(C)CC(N[C@@H](CC(C)C)C(N[C@H](C(N)=O)CCSC)=O)=O)=O)CC3=CC=CC=C3)=O)CC4=CC=CC=C4)=O)=O)=O)=O.CC(O)=O
Relative Density.1.31g/cm3
ColorWhite
AppearanceSolid
SequenceArg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-{SAR}-Leu-Met-NH2
Sequence ShortRPKPQQFF-{SAR}-LM-NH2
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 10 mM, Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM0.7034 mL3.5169 mL7.0338 mL35.1689 mL
5 mM0.1407 mL0.7034 mL1.4068 mL7.0338 mL
10 mM0.0703 mL0.3517 mL0.7034 mL3.5169 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
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Keywords

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