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TACI Protein, Human, Recombinant (His)

Catalog No. TMPY-02096
Synonyms: RYZN, IGAD2, CVID, TACI, TNFRSF14B, CVID2, tumor necrosis factor receptor superfamily, member 13B, CD267

TACI Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14.8 kDa and the accession number is O14836-2.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
TACI Protein, Human, Recombinant (His)
Pack Size Availability Price/USD Quantity
100 μg In stock $ 386.00
200 μg 5 days $ 682.00
500 μg 5 days $ 1,440.00
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Biological Description
Technical Params
Product Properties
References and Literature
Biological Information Testing in progress
Description TACI Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14.8 kDa and the accession number is O14836-2.
Species Human
Expression System HEK293 Cells
Tag C-His
Accession Number O14836-2
Synonyms RYZN, IGAD2, CVID, TACI, TNFRSF14B, CVID2, tumor necrosis factor receptor superfamily, member 13B, CD267
Construction The Human TNFRSF13B isoform 2 (O14836-2) extracellular domain (Ser 2-Thr 120) was expressed, with a polyhistidine tag at the C-terminus and a signal peptide at the N-terminus.
Protein Purity > 90 % as determined by SDS-PAGE

Molecular Weight 14.8 kDa (predicted)
Endotoxin < 1.0 EU/μg of the protein as determined by the LAL method.
Formulation Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Stability & Storage

It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted protein solutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

Shipping

In general, Lyophilized powders are shipping with blue ice.

Research Background Tumor necrosis factor receptor superfamily, member 13B (TNFRSF13B) also known as Transmembrane activator and CAML interactor (TACI) and CD267 antigen, is a member of the tumor necrosis factor receptor superfamily. TNFRSF13B is a trimeric cytokine receptor that binds tumor necrosis factors (TNF). The receptor cooperates with an adaptor protein which is important in determining the outcome of the response. Members of the TNF receptor superfamily (TNFRSF) have crucial roles in both innate and adaptive immunity and in cellular apoptosis process. Apoptosis is a cell suicide mechanism that enables metazoans to control cell number in tissues and to eliminate individual cells that threaten the animal's survival. Certain cells have unique sensors, termed death receptors or tumour necrosis factor (TNFR), on their surface. Tumour necrosis factors (TNFR) detect the presence of extracellular death signals and, in response, they rapidly ignite the cell's intrinsic apoptosis machinery. TACI/TNFRSF13B/CD267 induces activation of the transcription factors NFAT, AP1, and NF-kappa-B and plays a crucial role in humoral immunity by interacting with a TNF ligand.

References and Literature

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Keywords

TACI Protein, Human, Recombinant (His) RYZN IGAD2 CVID TACI TNFRSF14B CVID2 CD 267 tumor necrosis factor receptor superfamily, member 13B CD-267 IGAD-2 CVID 2 CD267 CVID-2 IGAD 2 recombinant recombinant-proteins proteins protein

 

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