ATG4A Protein, Human, Recombinant (His)

Name: ATG4A Protein, Human, Recombinant (His)
Brand: TargetMol
SKU: TMPJ-01250
Rating: 4.5 (1 reviews)

(Synonyms: hAPG4A, Cysteine Protease ATG4A, Autophagy-Related Protein 4 Homolog A, Autophagy-Related Cysteine Endopeptidase 2, Autophagin-2, AUT-Like 2 Cysteine Endopeptidase, AUTL2, ATG4A, APG4A) Copy Product Info

Synonyms: hAPG4A, Cysteine Protease ATG4A, Autophagy-Related Protein 4 Homolog A, Autophagy-Related Cysteine Endopeptidase 2, Autophagin-2, AUT-Like 2 Cysteine Endopeptidase, AUTL2, ATG4A, APG4A

Catalog No. TMPJ-01250 Copy Product Info

Cysteine Protease ATG4A (ATG4A) is a cytoplasmic protein that belongs to the peptidase C54 family. ATG4A is widely expressed in many tissues at a low level, but the highest expression is observed in skeletal muscle and brain. ATG4A is a cysteine protease required for autophagy; it cleaves the C-terminal part of MAP1LC3, GABARAPL2 or GABARAP. ATG4A is inhibited by N-ethylmaleimide. It is suggested that ATG4A has a significant role in suppressing various cancers.

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Pack Size	Price	USA Stock	Global Stock
10 µg	$183	35 days	35 days
20 µg	$292	35 days	35 days
50 µg	$545	35 days	35 days
100 µg	$813	35 days	35 days
200 µg	$1,190	35 days	35 days
500 µg	$2,070	35 days	35 days
1 mg	$2,970	35 days	35 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	Cysteine Protease ATG4A (ATG4A) is a cytoplasmic protein that belongs to the peptidase C54 family. ATG4A is widely expressed in many tissues at a low level, but the highest expression is observed in skeletal muscle and brain. ATG4A is a cysteine protease required for autophagy; it cleaves the C-terminal part of MAP1LC3, GABARAPL2 or GABARAP. ATG4A is inhibited by N-ethylmaleimide. It is suggested that ATG4A has a significant role in suppressing various cancers.
Species	Human
Expression System	E. coli
Tag	N-6xHis
Accession Number	Q8WYN0
Amino Acid	Met1-Val398
Construction	Met1-Val398
Protein Purity	Greater than 80% as determined by reducing SDS-PAGE. (QC verified)
Endotoxin	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation	Supplied as a 0.2 μm filtered solution of PBS, pH 7.4.
Synonyms	hAPG4A, Cysteine Protease ATG4A, Autophagy-Related Protein 4 Homolog A, Autophagy-Related Cysteine Endopeptidase 2, Autophagin-2, AUT-Like 2 Cysteine Endopeptidase, AUTL2, ATG4A, APG4A
Research Background	Cysteine Protease ATG4A (ATG4A) is a cytoplasmic protein that belongs to the peptidase C54 family. ATG4A is widely expressed in many tissues at a low level, but the highest expression is observed in skeletal muscle and brain. ATG4A is a cysteine protease required for autophagy; it cleaves the C-terminal part of MAP1LC3, GABARAPL2 or GABARAP. ATG4A is inhibited by N-ethylmaleimide. It is suggested that ATG4A has a significant role in suppressing various cancers.

Chemical Properties

Molecular Weight

40-55 KDa (reducing condition)

Storage & Solubility Information

Shipping	Proteins are shipped with blue ice.
Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.