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Anti-8-Hydroxy-2'-deoxyguanosine Polyclonal Antibody
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Catalog No. TMAB-00014
Anti-8-Hydroxy-2'-deoxyguanosine Polyclonal Antibody is a Rabbit antibody targeting 8-Hydroxy-2'-deoxyguanosine. Anti-8-Hydroxy-2'-deoxyguanosine Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Anti-8-Hydroxy-2'-deoxyguanosine Polyclonal Antibody
Anti-8-Hydroxy-2'-deoxyguanosine Polyclonal Antibody
😃Good
Catalog No. TMAB-00014
Anti-8-Hydroxy-2'-deoxyguanosine Polyclonal Antibody is a Rabbit antibody targeting 8-Hydroxy-2'-deoxyguanosine. Anti-8-Hydroxy-2'-deoxyguanosine Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $220 | 7-10 days | |
| 100 μL | $372 | 7-10 days | |
| 200 μL | $527 | 7-10 days |
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Antibody Type: Rabbit Polyclonal Application: IHC-P,IHC-Fr,IF Reactivity: Rat,Species independent |
| Ig Type | IgG |
| Reactivity | Rat,Species independent |
| Verified Activity | Tissue/cell: rat brain tissue (left panel was injury,Right panel was normal); 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer (0.01M, pH6.0), Boiling bathing for 15 min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30 min; Blocking buffer (normal goat serum) at 37°C for 20 min; Incubation: Anti-8-OHdG Polyclonal Antibody, Unconjugated (TMAB-00014) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody and DAb staining. |
| Application | IHC-P,IHC-Fr,IF |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Construction | Hybridoma Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Research Background | 8-Hydroxydeoxyguanosine (8OHdG) is a modified base that occurs in DNA due to attack by hydroxyl radicals that are formed as byproducts and intermediates of aerobic metabolism and during oxidative stress. There is increasing evidence to support the involvement of free radical reactions in the damage of biomolecules that eventually lead to several diseases in humans, such as atherosclerosis, cerebral and heart ischemia-reperfusion injury, cancer, rheumatoid arthritis, inflammation, diabetes, aging, and neurodegenerative conditions, such as Alzheimer's disease. |
| Immunogen | KLH conjugated 8-OHdG |
| Biology Area | Oxidative Stress,DNA / Nucleotides,Oxidative stress |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
Sci Citations
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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