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Anti-IGF2BP1 Polyclonal Antibody

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Catalog No. TMAB-00921
Alias Zipcode binding protein 1, Zip code-binding protein 1, Zip code binding protein 1, ZBP-1, ZBP1, VICKZ1, VICKZ family member 1, Insulin-like growth factor 2 mRNA-binding protein 1, IMP-1, IMP1, IGF-II mRNA-binding protein 1, IGF2BP1, IGF2 mRNA-binding protein 1, IF2B1, CRD-BP, CRDBP, CRD BP, Coding region determinant-binding protein

Anti-IGF2BP1 Polyclonal Antibody is a Rabbit antibody targeting IGF2BP1. Anti-IGF2BP1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-IGF2BP1 Polyclonal Antibody

Anti-IGF2BP1 Polyclonal Antibody

😃Good
Catalog No. TMAB-00921Alias Zipcode binding protein 1, Zip code-binding protein 1, Zip code binding protein 1, ZBP-1, ZBP1, VICKZ1, VICKZ family member 1, Insulin-like growth factor 2 mRNA-binding protein 1, IMP-1, IMP1, IGF-II mRNA-binding protein 1, IGF2BP1, IGF2 mRNA-binding protein 1, IF2B1, CRD-BP, CRDBP, CRD BP, Coding region determinant-binding protein
Anti-IGF2BP1 Polyclonal Antibody is a Rabbit antibody targeting IGF2BP1. Anti-IGF2BP1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Pack SizePriceAvailabilityQuantity
50 μL$2227-10 days
100 μL$3737-10 days
200 μL$5277-10 days
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Product Introduction

Bioactivity
Description
Anti-IGF2BP1 Polyclonal Antibody is a Rabbit antibody targeting IGF2BP1. Anti-IGF2BP1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
AliasZipcode binding protein 1, Zip code-binding protein 1, Zip code binding protein 1, ZBP-1, ZBP1, VICKZ1, VICKZ family member 1, Insulin-like growth factor 2 mRNA-binding protein 1, IMP-1, IMP1, IGF-II mRNA-binding protein 1, IGF2BP1, IGF2 mRNA-binding protein 1, IF2B1, CRD-BP, CRDBP, CRD BP, Coding region determinant-binding protein
Ig Type
IgG
Reactivity
Human,Mouse,Rat (predicted:Chicken,Dog,Pig,Cow,Horse,Rabbit,Zebrafish,Sheep)
Verified Activity
1. Tissue/cell: mouse embryo tissue; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer (0.01M, pH6.0), Boiling bathing for 15 min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30 min; Blocking buffer (normal goat serum) at 37°C for 20 min;
Incubation: Anti-IGF2BP1 Polyclonal Antibody, Unconjugated (TMAB-00921) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody and DAb staining.
2. Paraformaldehyde-fixed, paraffin embedded (rat lung); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 min; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (IGF2BP1) Polyclonal Antibody, Unconjugated (TMAB-00921) at 1:200 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructionsand DAB staining.
3. Paraformaldehyde-fixed, paraffin embedded (rat testis); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 min; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (IGF2BP1) Polyclonal Antibody, Unconjugated (TMAB-00921) at 1:200 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructionsand DAB staining.
4. Paraformaldehyde-fixed, paraffin embedded (human colon carcinoma); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 min; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (IGF2BP1) Polyclonal Antibody, Unconjugated (TMAB-00921) at 1:200 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructionsand DAB staining.
5. Paraformaldehyde-fixed, paraffin embedded (human tonsil); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 min; Blocking buffer (normal goat serum) at 37°C for 30 min; Incubation with (IGF2BP1) Polyclonal Antibody, Unconjugated (TMAB-00921) at 1:200 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructionsand DAB staining.
Application
IHC-P,IHC-Fr,IF
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationNucleus. Cytoplasm. Cell projection, lamellipodium. Cell projection, dendrite (By similarity). Cell projection, dendritic spine (By similarity). Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs. Targeted to stress granules (SGs), but not processing bodies (PBs), during cellular stress. Colocalizes with G3BP1 and TIAL1 in SGs. Colocalizes with HIV-1 GAG at the cell edges. Found in lamellipodia of the leading edge, in the perinuclear region, and beneath the plasma membrane. The subcytoplasmic localization is cell specific and regulated by cell contact and growth. Colocalized with H19 RNA at lamellipodia. Colocalized with CD44 mRNA in RNP granules. Nuclear export is mediated by XPO1/CRM1. In motile cells, is transported towards the leading edge into the cortical region of the lamellipodia where it is connected to microfilaments (By similarity). Present in the form of granules and into F-actin-rich protrusion of dendrites, spines and subsynaptic sites (By similarity). Colocalizes with beta-actin mRNA in dendrites and spines (By similarity). Exhibited rapid, bidirectional movements in dendrites and spines (By similarity). Neuronal depolarization by KCl induces its rapid efflux from the cell body into dendrites (By similarity).
ConstructionHybridoma Polyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human IGF2BP1/IMP1
Antigen Species
Human
Gene ID
Uniprot ID
Biology Area
Nuclear Pore Complex
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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