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Epoxiconazole
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Catalog No. T19721Cas No. 133855-98-8
Alias EC-406-850-2, EC 406 850 2, BAS-480F, BAS480F, BAS 480F
Epoxiconazole (BAS-480F) is a 14-α demethylase inhibitor. It inhibits ergosterol synthesis and fungal cell wall formation.
Epoxiconazole
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Purity: 98.57%
Catalog No. T19721Alias EC-406-850-2, EC 406 850 2, BAS-480F, BAS480F, BAS 480FCas No. 133855-98-8
Epoxiconazole (BAS-480F) is a 14-α demethylase inhibitor. It inhibits ergosterol synthesis and fungal cell wall formation.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 10 mg | $41 | In Stock | In Stock | |
| 25 mg | $74 | In Stock | In Stock | |
| 50 mg | $97 | In Stock | In Stock | |
| 100 mg | $157 | In Stock | In Stock | |
| 200 mg | $237 | - | In Stock | |
| 1 mL x 10 mM (in DMSO) | $30 | In Stock | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information
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Purity:98.57%
Appearance:Solid
Color:White
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Product Introduction
Epoxiconazole AI Summary
Epoxiconazole exhibits broad-spectrum antifungal activity, targeting a variety of fungal pathogens including Fusarium graminearum, Zymoseptoria tritici, Oculimacula yallundae, and Oculimacula acuformis. Against Fusarium graminearum, it shows significant growth inhibition at a concentration of 10^-4 M after 14 days and notable antifungal activity within 8 hours, with an EC50 value of 10800000.0 nM. For Zymoseptoria tritici, EC50 values range from 0.0015 to 1.41 ug/mL, demonstrating variable potency across different strains and genetic backgrounds. Furthermore, it effectively inhibits germ tube elongation and mycelial growth of Oculimacula species, including resistant strains, with a higher selectivity towards Oculimacula acuformis. The compound also has a low toxicity profile in Rattus norvegicus (LD50 of 3160.0 mg.kg^-1) and exhibits low solubility at 0.7 mg per 100 g. Overall, Epoxiconazole holds promise for controlling a wide range of fungal pathogens, including those resistant to other fungicidal agents..
Note: Summary generated by AI. Data source: ChEMBL 
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Epoxiconazole (BAS-480F) is a 14-α demethylase inhibitor. It inhibits ergosterol synthesis and fungal cell wall formation. |
| Synonyms | EC-406-850-2, EC 406 850 2, BAS-480F, BAS480F, BAS 480F |
| Molecular Weight | 329.76 |
| Formula | C17H13ClFN3O |
| Cas No. | 133855-98-8 |
| Smiles | Fc1ccc(cc1)[C@@]1(Cn2cncn2)O[C@@H]1c1ccccc1Cl |
| Relative Density. | 1.39 g/cm3 (Predicted) |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 142.8 mg/mL (433.04 mM), Sonication is recommended.  | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
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Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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