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Pimivalimab
(Synonyms: JTX-4014) Copy Product Info
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Synonyms: JTX-4014
Catalog No. T77164 Copy Product Info
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Pimivalimab (JTX-4014) is a high-affinity, fully human IgG4 monoclonal antibody targeting the cell surface receptor PD-1. By blocking the interaction between PD-1 and its ligands PD-L1 and PD-L2, the antibody reverses the immunosuppressed state of T cells and enhances the anti-tumor immune response against various solid tumors. It is frequently studied as a monotherapy or in combination with other therapies, such as LILRB2 inhibitors.
Pimivalimab
Cas No. 2293951-22-9
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 mg | Inquiry | Inquiry | Inquiry |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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With extensive experience in compound synthesis, we can provide rapid custom synthesis services for this product according to your research needs.
For research use only—not for human use. No sales to individuals. Use as intended only.
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| Description | Pimivalimab (JTX-4014) is a high-affinity, fully human IgG4 monoclonal antibody targeting the cell surface receptor PD-1. By blocking the interaction between PD-1 and its ligands PD-L1 and PD-L2, the antibody reverses the immunosuppressed state of T cells and enhances the anti-tumor immune response against various solid tumors. It is frequently studied as a monotherapy or in combination with other therapies, such as LILRB2 inhibitors. |
| Synonyms | JTX-4014 |
| Reactivity | Human |
| Application | FACS Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Uniprot ID | |
| Target | PD-1 |
| Cas No. | 2293951-22-9 |
| Isotype | IgG4 (S228P) |
| Recommended Isotype Control |
| Storage | Store at low temperature Store at -20°C Shipping with blue ice/Shipping at ambient temperature. |
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