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Phen-DC3

Name: Phen-DC3
Brand: TargetMol
SKU: T13817
Rating: 4.5 (1 reviews)

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Catalog No. T13817Cas No. 942936-75-6

Phen-DC3 is a G-quadruplex (G4) specific ligand that inhibits FANCJ and DinG helicases with IC50 values of 65±6 nM and 50±10 nM, respectively.

Phen-DC3

😃Good

Catalog No. T13817Cas No. 942936-75-6

Phen-DC3 is a G-quadruplex (G4) specific ligand that inhibits FANCJ and DinG helicases with IC50 values of 65±6 nM and 50±10 nM, respectively.

Pack Size	Price	USA Warehouse	Global Warehouse
25 mg	$1,520	6-8 weeks	6-8 weeks
50 mg	$1,980	6-8 weeks	6-8 weeks
100 mg	$2,500	6-8 weeks	6-8 weeks

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Product Introduction

Bioactivity

Description	Phen-DC3 is a G-quadruplex (G4) specific ligand that inhibits FANCJ and DinG helicases with IC50 values of 65±6 nM and 50±10 nM, respectively.
Targets&IC50	FANCJ helicase (G4 substrate):65±6 nM , DinG helicases (G4 substrate):50±10 nM

Chemical Properties

Molecular Weight	550.61
Formula	C₃₄H₂₆N₆O₂
Cas No.	942936-75-6
Smiles	C(NC1=CC2=C([N+](C)=C1)C=CC=C2)(=O)C3=NC4=C5C(=CC=C4C=C3)C=CC(C(NC6=CC7=C([N+](C)=C6)C=CC=C7)=O)=N5
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 34 mg/mL (61.75 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.8162 mL	9.0808 mL	18.1617 mL	90.8084 mL
5 mM	0.3632 mL	1.8162 mL	3.6323 mL	18.1617 mL
10 mM	0.1816 mL	0.9081 mL	1.8162 mL	9.0808 mL
20 mM	0.0908 mL	0.4540 mL	0.9081 mL	4.5404 mL
50 mM	0.0363 mL	0.1816 mL	0.3632 mL	1.8162 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline /PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Stock solution preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(stock solution concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline /PBS/ddH₂O TargetMol | reagent

mix well and clarify

The above example illustrates how to use "In Vivo Formulation Calculator" and does not represent a recommended formulation for any specific compound. Please select an appropriate dissolution method based on your experimental animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc