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Anti-Integrin alpha 2 Antibody (8P138)
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Catalog No. TMAB-00979
Alias VLA2 alpha chain, VLA 2 subunit alpha, VLA 2 alpha chain, VLA 2, Very late activation protein 2 receptor alpha 2 subunit, Platelet receptor for collagen, deficiency of, included, Platelet membrane glycoprotein Ia, Platelet glycoprotein Ia/Iia, Platelet glycoprotein Ia, Platelet glycoprotein GPIa, Platelet antigen Br, Platelet alloantigen Br(a), included, Itga2, ITA2, HPA5 included, HPA 5 included, GPIa, GP Ia deficiency, included, GP Ia, Glycoprotein Ia deficiency included, DX5, Collagen receptor, CD49b antigen, CD49b, CD49 antigen like family member B, CD 49b
Anti-Integrin alpha 2 Antibody (8P138) is a Rabbit antibody targeting Integrin alpha 2. Anti-Integrin alpha 2 Antibody (8P138) can be used in IF,IHC-Fr,IHC-P,WB.
Anti-Integrin alpha 2 Antibody (8P138)
Anti-Integrin alpha 2 Antibody (8P138)
😃Good
Catalog No. TMAB-00979Alias VLA2 alpha chain, VLA 2 subunit alpha, VLA 2 alpha chain, VLA 2, Very late activation protein 2 receptor alpha 2 subunit, Platelet receptor for collagen, deficiency of, included, Platelet membrane glycoprotein Ia, Platelet glycoprotein Ia/Iia, Platelet glycoprotein Ia, Platelet glycoprotein GPIa, Platelet antigen Br, Platelet alloantigen Br(a), included, Itga2, ITA2, HPA5 included, HPA 5 included, GPIa, GP Ia deficiency, included, GP Ia, Glycoprotein Ia deficiency included, DX5, Collagen receptor, CD49b antigen, CD49b, CD49 antigen like family member B, CD 49b
Anti-Integrin alpha 2 Antibody (8P138) is a Rabbit antibody targeting Integrin alpha 2. Anti-Integrin alpha 2 Antibody (8P138) can be used in IF,IHC-Fr,IHC-P,WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 25 μL | $155 | 7-10 days | |
| 50 μL | $273 | 7-10 days | |
| 100 μL | $489 | 7-10 days |
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-Integrin alpha 2 Antibody (8P138) is a Rabbit antibody targeting Integrin alpha 2. Anti-Integrin alpha 2 Antibody (8P138) can be used in IF,IHC-Fr,IHC-P,WB. |
| Synonyms | VLA2 alpha chain, VLA 2 subunit alpha, VLA 2 alpha chain, VLA 2, Very late activation protein 2 receptor alpha 2 subunit, Platelet receptor for collagen, deficiency of, included, Platelet membrane glycoprotein Ia, Platelet glycoprotein Ia/Iia, Platelet glycoprotein Ia, Platelet glycoprotein GPIa, Platelet antigen Br, Platelet alloantigen Br(a), included, Itga2, ITA2, HPA5 included, HPA 5 included, GPIa, GP Ia deficiency, included, GP Ia, Glycoprotein Ia deficiency included, DX5, Collagen receptor, CD49b antigen, CD49b, CD49 antigen like family member B, CD 49b |
| Ig Type | IgG |
| Clone | 8P138 |
| Reactivity | Human,Mouse,Rat |
| Verified Activity | 1. 25 μg total protein per Lane of various lysates probed with Integrin alpha 2 monoclonal antibody, unconjugated (TMAB-00979) at 1:2000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at RT for 60 min. 2. Paraformaldehyde-fixed, paraffin embedded Rat Colon; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with Integrin alpha 2 Monoclonal Antibody, Unconjugated (TMAB-00979) at 1:200 overnight at 4°C, followed by conjugation to the SP Kit (Rabbit) and DAB staining. 3. Paraformaldehyde-fixed, paraffin embedded Mouse Colon; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with Integrin alpha 2 Monoclonal Antibody, Unconjugated (TMAB-00979) at 1:200 overnight at 4°C, followed by conjugation to the SP Kit (Rabbit) and DAB staining. 4. Paraformaldehyde-fixed, paraffin embedded Human Colon; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with Integrin alpha 2 Monoclonal Antibody, Unconjugated (TMAB-00979) at 1:200 overnight at 4°C, followed by conjugation to the SP Kit (Rabbit) and DAB staining. 5. Paraformaldehyde-fixed, paraffin embedded Human Cervical Cancer; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with Integrin alpha 2 Monoclonal Antibody, Unconjugated (TMAB-00979) at 1:200 overnight at 4°C, followed by conjugation to the SP Kit (Rabbit) and DAB staining. |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:50-200; IHC-Fr: 1:50-200; IF: 1:50-200 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Membrane; Single-pass type I membrane protein. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | Enables amyloid-beta binding activity. Predicted to be involved in several processes, including cell surface receptor signaling pathway; positive regulation of cell migration; and positive regulation of cellular component organization. Predicted to act upstream of or within cell adhesion. Located in basal part of cell and external side of plasma membrane. Is expressed in several structures, including alimentary system; brain; cardiovascular system; eye; and genitourinary system. Human ortholog(s) of this gene implicated in several diseases, including Behcet's disease; artery disease (multiple); blood platelet disease (multiple); diabetes mellitus (multiple); and von Willebrand's disease (multiple). Orthologous to human ITGA2 (integrin subunit alpha 2). [provided by Alliance of Genome Resources, Apr 2022] |
| Immunogen | A synthesized peptide: human Integrin alpha 2 |
| Antigen Species | Human |
| Gene Name | ITGA2 |
| Gene ID | |
| Protein Name | Integrin alpha-2 |
| Uniprot ID | |
| Biology Area | Response to hypoxia,Hypoxia,Alpha |
| Function | Integrin alpha-2/beta-1 is a receptor for laminin, collagen, collagen C-propeptides, fibronectin and E-cadherin. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. It is responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix. |
| Molecular Weight | Theoretical: 127 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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