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Anti-Phospho-MAPK14 (Tyr182) Polyclonal Antibody (Synonyms: p-MAPK14 (Y182), p-MAPK14 (Tyr182), MAPK14 (p-Y182...)

Catalog No. TMAC-02959 Copy Product Info
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Anti-Phospho-MAPK14 (Tyr182) Polyclonal Antibody is a Rabbit antibody targeting Phospho-MAPK14 (Tyr182). Anti-Phospho-MAPK14 (Tyr182) Polyclonal Antibody can be used in IHC,WB.

Anti-Phospho-MAPK14 (Tyr182) Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAC-02959
Synonyms p-MAPK14 (Y182), p-MAPK14 (Tyr182), MAPK14 (p-Y182), MAPK14 (p-Tyr182)

Anti-Phospho-MAPK14 (Tyr182) Polyclonal Antibody is a Rabbit antibody targeting Phospho-MAPK14 (Tyr182). Anti-Phospho-MAPK14 (Tyr182) Polyclonal Antibody can be used in IHC,WB.

Anti-Phospho-MAPK14
(Tyr182) Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2177-10 days7-10 days
100 μL$3167-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Phospho-MAPK14 (Tyr182) Polyclonal Antibody is a Rabbit antibody targeting Phospho-MAPK14 (Tyr182). Anti-Phospho-MAPK14 (Tyr182) Polyclonal Antibody can be used in IHC,WB.
Synonymsp-MAPK14 (Y182), p-MAPK14 (Tyr182), MAPK14 (p-Y182), MAPK14 (p-Tyr182)
Ig Type
IgG
Reactivity
Human,Mouse,Rat
Verified Activity
1. Western blot analysis of extracts from Hela cells untreated or treated with UV for the indicated times, using P38 MAPK (Phospho-Tyr182) Antibody TMAC-02959.
2. Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using P38 MAPK (Phospho-Tyr182) Antibody TMAC-02959 (left) or the same antibody preincubated with blocking peptide (right).
3. Western blot analysis of extracts from Hela cells, treated with TNFa or calf intestinal phosphatase (CIP), using P38 MAPK (Phospho-Tyr182) Antibody TMAC-02959.
verifiedActivityverifiedActivityverifiedActivity
Application
Antibody Type
Polyclonal
Host SpeciesRabbit
ConstructionPolyclonal Antibody
PurificationAntibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
AppearanceLiquid
FormulationSupplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Research BackgroundResponds to activation by environmental stress, pro-inflammatory cytokines and lipopolysaccharide (LPS) by phosphorylating a number of transcription factors, such as ELK1 and ATF2 and several downstream kinases, such as MAPKAPK2 and MAPKAPK5. Plays a critical role in the production of some cytokines, for example IL-6. May play a role in stabilization of EPO mRNA during hypoxic stress. Isoform Mxi2 activation is stimulated by mitogens and oxidative stress and only poorly phosphorylates ELK1 and ATF2. Isoform Exip may play a role in the early onset of apoptosis.
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
Phospho
Antigen Details
Immunogen
Peptide sequence around phosphorylation site of tyrosine 182 (T-G-Y(p)-V-A) derived from Human P38 MAPK
Antigen Species
human
Uniprot ID
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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