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PADI4 Protein, Human, Recombinant (E. coli, His)

Catalog No. TMPJ-00532
Synonyms: PDI5, PADI4, Protein-arginine Deiminase type IV, HL-60 PAD, PADI5, Protein-Arginine Deiminase Type-4, Peptidylarginine Deiminase IV

Protein-Arginine Deiminase Type-4 (PADI4) belongs to the Protein Arginine Deiminase family. PADI4 is expressed in eosinophils and neutrophils, but it is not expressed in peripheral monocytes or lymphocytes. PADI4 catalyzes the citrullination/deimination of arginine residues of proteins. In addition, PADI4 may play an important role in tumourigenesis. Genetic variations in PADI4 are a cause of susceptibility to rheumatoid arthritis (RA), which is a systemic inflammatory disease with autoimmune features and a complex genetic component.

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PADI4 Protein, Human, Recombinant (E. coli, His)
Pack Size Availability Price/USD Quantity
10 μg 5 days $ 184.00
50 μg 5 days $ 545.00
500 μg 5 days $ 2,070.00
1 mg 5 days $ 2,970.00
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Biological Description
Technical Params
Product Properties
Description Protein-Arginine Deiminase Type-4 (PADI4) belongs to the Protein Arginine Deiminase family. PADI4 is expressed in eosinophils and neutrophils, but it is not expressed in peripheral monocytes or lymphocytes. PADI4 catalyzes the citrullination/deimination of arginine residues of proteins. In addition, PADI4 may play an important role in tumourigenesis. Genetic variations in PADI4 are a cause of susceptibility to rheumatoid arthritis (RA), which is a systemic inflammatory disease with autoimmune features and a complex genetic component.
Species Human
Expression System E. coli
Tag N-6His
Accession Number AAH25718.1
Synonyms PDI5, PADI4, Protein-arginine Deiminase type IV, HL-60 PAD, PADI5, Protein-Arginine Deiminase Type-4, Peptidylarginine Deiminase IV
Amino Acid Met1-Pro663
Construction Recombinant Human Protein-Arginine Deiminase Type-4 is produced by our E.coli expression system and the target gene encoding Met1-Pro663 is expressed with a 6His tag at the N-terminus.
Protein Purity Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Molecular Weight 78 KDa, reducing conditions
Endotoxin Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation Supplied as a 0.2 μm filtered solution of 50mM Tris-HCl, 500mM NaCl, pH 7.5.
Stability & Storage

Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

Shipping

The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below.

Research Background Protein-Arginine Deiminase Type-4 (PADI4) belongs to the Protein Arginine Deiminase family. PADI4 is expressed in eosinophils and neutrophils, but it is not expressed in peripheral monocytes or lymphocytes. PADI4 catalyzes the citrullination/deimination of arginine residues of proteins. In addition, PADI4 may play an important role in tumourigenesis. Genetic variations in PADI4 are a cause of susceptibility to rheumatoid arthritis (RA), which is a systemic inflammatory disease with autoimmune features and a complex genetic component.

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Keywords

PADI4 Protein, Human, Recombinant (E. coli, His) PADI 5 PDI5 PADI4 Protein-arginine Deiminase type IV PDI 5 HL-60 PAD PADI5 PDI-5 PADI 4 Protein-Arginine Deiminase Type-4 Peptidylarginine Deiminase IV PADI-4 PADI-5 recombinant recombinant-proteins proteins protein

 

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