PADI4 Protein, Human, Recombinant (E. coli, His)

Name: PADI4 Protein, Human, Recombinant (E. coli, His)
Brand: TargetMol
SKU: TMPJ-00532
Rating: 4.5 (1 reviews)

(Synonyms: Protein-Arginine Deiminase Type-4, Protein-arginine Deiminase type IV, Peptidylarginine Deiminase IV, PDI5, PADI5, PADI4, HL-60 PAD) Copy Product Info

Synonyms: Protein-Arginine Deiminase Type-4, Protein-arginine Deiminase type IV, Peptidylarginine Deiminase IV, PDI5, PADI5, PADI4, HL-60 PAD

Catalog No. TMPJ-00532 Copy Product Info

Protein-Arginine Deiminase Type-4 (PADI4) belongs to the Protein Arginine Deiminase family. PADI4 is expressed in eosinophils and neutrophils, but it is not expressed in peripheral monocytes or lymphocytes. PADI4 catalyzes the citrullination/deimination of arginine residues of proteins. In addition, PADI4 may play an important role in tumourigenesis. Genetic variations in PADI4 are a cause of susceptibility to rheumatoid arthritis (RA), which is a systemic inflammatory disease with autoimmune features and a complex genetic component.

PADI4 Protein, Human, Recombinant (E. coli, His)

Pack Size	Price	USA Stock	Global Stock
10 µg	$183	7-10 days	7-10 days
20 µg	$292	7-10 days	7-10 days
50 µg	$545	7-10 days	7-10 days
100 µg	$813	7-10 days	7-10 days
200 µg	$1,190	7-10 days	7-10 days
500 µg	$2,070	7-10 days	7-10 days
1 mg	$2,970	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Batch Information

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Purity:Greater than 95% as determined by reducing SDS-PAGE.

Appearance:Solution

Color:Transparent

Resource Download

COA User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	Protein-Arginine Deiminase Type-4 (PADI4) belongs to the Protein Arginine Deiminase family. PADI4 is expressed in eosinophils and neutrophils, but it is not expressed in peripheral monocytes or lymphocytes. PADI4 catalyzes the citrullination/deimination of arginine residues of proteins. In addition, PADI4 may play an important role in tumourigenesis. Genetic variations in PADI4 are a cause of susceptibility to rheumatoid arthritis (RA), which is a systemic inflammatory disease with autoimmune features and a complex genetic component.
Species	Human
Expression System	E. coli
Tag	N-6xHis
Accession Number	AAH25718.1
Amino Acid	Met1-Pro663
Construction	Met1-Pro663
Protein Purity	Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Endotoxin	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation	Supplied as a 0.2 μm filtered solution of 50 mM Tris-HCl, 500 mM NaCl, pH 7.5.
Synonyms	Protein-Arginine Deiminase Type-4, Protein-arginine Deiminase type IV, Peptidylarginine Deiminase IV, PDI5, PADI5, PADI4, HL-60 PAD
Research Background	Protein-Arginine Deiminase Type-4 (PADI4) belongs to the Protein Arginine Deiminase family. PADI4 is expressed in eosinophils and neutrophils, but it is not expressed in peripheral monocytes or lymphocytes. PADI4 catalyzes the citrullination/deimination of arginine residues of proteins. In addition, PADI4 may play an important role in tumourigenesis. Genetic variations in PADI4 are a cause of susceptibility to rheumatoid arthritis (RA), which is a systemic inflammatory disease with autoimmune features and a complex genetic component.

Chemical Properties

Molecular Weight

78 KDa (reducing condition)

Storage & Solubility Information

Shipping	Proteins are shipped with blue ice.
Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.