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Anti-E-Cadherin/Cadherin-1 Polyclonal Antibody 3
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Catalog No. TMAB-00586
Anti-E-Cadherin/Cadherin-1 Polyclonal Antibody 3 is a Rabbit antibody targeting E-Cadherin/Cadherin-1. Anti-E-Cadherin/Cadherin-1 Polyclonal Antibody 3 can be used in WB,FCM.
Anti-E-Cadherin/Cadherin-1 Polyclonal Antibody 3
Anti-E-Cadherin/Cadherin-1 Polyclonal Antibody 3
😃Good
Catalog No. TMAB-00586
Anti-E-Cadherin/Cadherin-1 Polyclonal Antibody 3 is a Rabbit antibody targeting E-Cadherin/Cadherin-1. Anti-E-Cadherin/Cadherin-1 Polyclonal Antibody 3 can be used in WB,FCM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $221 | 7-10 days | |
| 100 μL | $372 | 7-10 days | |
| 200 μL | $528 | 7-10 days |
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Antibody Type: Rabbit Polyclonal Application: WB,FCM Reactivity: Human (predicted:Horse,Cow,Pig,Dog,Chicken,Rat,Mouse) |
| Ig Type | IgG |
| Reactivity | Human (predicted:Horse,Cow,Pig,Dog,Chicken,Rat,Mouse) |
| Verified Activity | 1. Histogram of MCF7 cells stained with anti-E-cadherin (orange), isotype control antibody (green), secondary antibody only (blue) and unstained (red). 2. Sample: Lane 1: MDA-MB-231 (Human) Cell Lysate at 30 μg Lane 2: A431 (Human) Cell Lysate at 30 μg Lane 3: A549 (Human) Cell Lysate at 30 μg Lane 4: HepG2 (Human) Cell Lysate at 30 μg Primary: Anti-E cadherin (TMAB-00586) at 1/500 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 125 kDa Observed band size: 120 kDa |
| Application | WB,FCM |
| Recommended Dose | WB: 1:500-2000; FCM: 1μg/Test |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cell junction. Cell membrane; Single-pass type I membrane protein. |
| Construction | Hybridoma Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Research Background | This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function of this gene is thought to contribute to cancer progression by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. This gene is present in a gene cluster with other members of the cadherin family on chromosome 16. [provided by RefSeq, Nov 2015] |
| Immunogen | KLH conjugated synthetic peptide: human E-cadherin |
| Antigen Species | Human |
| Gene ID | 999 |
| Uniprot ID | |
| Biology Area | Cadherins,Kidney development,e cadherin,Cadherins,Calcium Binding Proteins |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
Sci Citations
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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