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Nectin-4 Protein, Human, Recombinant (His & Avi)

Catalog No. TMPK-00308
Synonyms: PVRL4, LNIR, NECTIN4, PRR4, EDSS1

Nectin-4 seems to be involved in cell adhesion through trans-homophilic and -heterophilic interactions, the latter including specifically interactions with NECTIN1. Does not act as receptor for alpha-herpesvirus entry into cells.(Microbial infection) Acts as a receptor for measles virus. Nectin-4 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 37.2 kDa and the accession number is Q96NY8.

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Nectin-4 Protein, Human, Recombinant (His & Avi)
Pack Size Availability Price/USD Quantity
100 μg 5 days $ 418.00
500 μg 5 days $ 1,670.00
1 mg 5 days $ 2,800.00
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Biological Description
Technical Params
Product Properties
References and Literature
Description Nectin-4 seems to be involved in cell adhesion through trans-homophilic and -heterophilic interactions, the latter including specifically interactions with NECTIN1. Does not act as receptor for alpha-herpesvirus entry into cells.(Microbial infection) Acts as a receptor for measles virus. Nectin-4 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 37.2 kDa and the accession number is Q96NY8.
Species Human
Expression System HEK293 Cells
Tag C-His-Avi
Accession Number Q96NY8
Synonyms PVRL4, LNIR, NECTIN4, PRR4, EDSS1
Construction Gly32-Val351
Protein Purity > 95% as determined by Tris-Bis PAGE; > 95% as determined by SEC-HPLC
Molecular Weight 37.2 kDa (predicted). Due to glycosylation, the protein migrates to 46-48 kDa based on Tris-Bis PAGE result.
Endotoxin < 1 EU/μg by the LAL method.
Formulation Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
Reconstitution Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Stability & Storage

It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

Shipping

In general, Lyophilized powders are shipping with blue ice.

Research Background Nectin-4 seems to be involved in cell adhesion through trans-homophilic and -heterophilic interactions, the latter including specifically interactions with NECTIN1. Does not act as receptor for alpha-herpesvirus entry into cells.(Microbial infection) Acts as a receptor for measles virus.

References and Literature

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Keywords

Nectin-4 Protein, Human, Recombinant (His & Avi) PVRL4 LNIR NECTIN4 PRR4 PRR-4 NECTIN 4 PRR 4 PVRL-4 NECTIN-4 EDSS 1 EDSS-1 PVRL 4 EDSS1 recombinant recombinant-proteins proteins protein

 

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