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IFN-alpha 1/IFNA1 Protein, Mouse, Recombinant (hFc)

(Synonyms: LeIF D, Interferon α-D, Interferon α-1/13, Interferon α1, Interferon alpha-D, Interferon alpha-1/13, Interferon alpha 1, IFN-α-1/13, IFN-α-1, IFNα1, IFN-alpha-1/13, IFN-alpha-1, IFNalpha 1, IFNA1, IFN α1, IFN α 1, IFN alpha1) Copy Product Info

Synonyms: LeIF D, Interferon α-D, Interferon α-1/13, Interferon α1, Interferon alpha-D, Interferon alpha-1/13, Interferon alpha 1, IFN-α-1/13, IFN-α-1, IFNα1, IFN-alpha-1/13, IFN-alpha-1, IFNalpha 1, IFNA1, IFN α1, IFN α 1, IFN alpha1

Catalog No. TMPK-00074 Copy Product Info
IFN-α, a cytokine expressed in human islets from individuals affected by type 1 diabetes, plays a key role in the pathogenesis of diabetes by upregulating inflammation, endoplasmic reticulum (ER) stress and MHC class I overexpression, three hallmarks of islet histology in early type 1 diabetes. IFN-alpha 1/IFNA1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 45.88 kDa and the accession number is P01572.
IFN-alpha 1/IFNA1 Protein, Mouse, Recombinant (hFc)
Pack SizePriceUSA StockGlobal StockQuantity
5 μg$58-In Stock
10 μg$92-In Stock
20 μg$1487-10 days7-10 days
50 μg$2897-10 days7-10 days
100 μg$487-In Stock
200 μg$8837-10 days7-10 days
500 μg$1,9507-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Batch Information

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Purity:> 95% as determined by Bis-Tris PAGE
Appearance:Lyophilized powder
Color:White
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Product Introduction

Bioactivity
Description
IFN-α, a cytokine expressed in human islets from individuals affected by type 1 diabetes, plays a key role in the pathogenesis of diabetes by upregulating inflammation, endoplasmic reticulum (ER) stress and MHC class I overexpression, three hallmarks of islet histology in early type 1 diabetes. IFN-alpha 1/IFNA1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 45.88 kDa and the accession number is P01572.
Species
Mouse
Expression System
HEK293 Cells
TagC-hFc
Accession NumberP01572
ConstructionCys24-Lys189
Protein Purity
> 95% as determined by Tris-Bis PAGE
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationLyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
ReconstitutionReconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Stability & StorageIt is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
SynonymsLeIF D, Interferon α-D, Interferon α-1/13, Interferon α1, Interferon alpha-D, Interferon alpha-1/13, Interferon alpha 1, IFN-α-1/13, IFN-α-1, IFNα1, IFN-alpha-1/13, IFN-alpha-1, IFNalpha 1, IFNA1, IFN α1, IFN α 1, IFN alpha1
Research Background
Chemical Properties
Molecular Weight45.88 kDa (predicted). Due to glycosylation, the protein migrates to 50-60 kDa based on Tris-Bis PAGE result.
Storage & Solubility Information
StorageStore at low temperature Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months

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Keywords

Related Tags: IFN-alpha 1/IFNA1 Protein, Mouse, Recombinant (hFc) chemical structure | IFN-alpha 1/IFNA1 Protein, Mouse, Recombinant (hFc) molecular weight