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Anti-CD40 Polyclonal Antibody
(Synonyms: TNFRSF5, p50, CDW40, CD40 molecule, TNF receptor superfamily member 5, Bp50) Copy Product Info
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Synonyms: TNFRSF5, p50, CDW40, CD40 molecule, TNF receptor superfamily member 5, Bp50
Catalog No. TMAB-00365 Copy Product Info
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Anti-CD40 Polyclonal Antibody is a Rabbit antibody targeting CD40. Anti-CD40 Polyclonal Antibody can be used in IF, IHC-Fr, IHC-P, WB.
Anti-CD40 Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-CD40 Polyclonal Antibody is a Rabbit antibody targeting CD40. Anti-CD40 Polyclonal Antibody can be used in IF, IHC-Fr, IHC-P, WB. |
| Synonyms | TNFRSF5, p50, CDW40, CD40 molecule, TNF receptor superfamily member 5, Bp50 |
| Ig Type | IgG |
| Reactivity | Human,Mouse (predicted:Rat,Chicken,Dog,Pig,Cow,Rabbit) |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Isoform I: Cell membrane; Single-pass type I membrane protein. Isoform II: Secreted. |
| Tissue Specificity | B-cells and in primary carcinomas. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | Predicted to enable antigen binding activity; protein domain specific binding activity; and ubiquitin protein ligase binding activity. Involved in B cell mediated immunity; CD40 signaling pathway; and cellular calcium ion homeostasis. Acts upstream of or within several processes, including defense response to other organism; positive regulation of B cell activation; and positive regulation of interleukin-12 production. Located in external side of plasma membrane and intracellular membrane-bounded organelle. Part of CD40 receptor complex. Is expressed in several structures, including alimentary system; brain; hemolymphoid system gland; liver and biliary system; and reproductive system. Human ortholog(s) of this gene implicated in several diseases, including Kawasaki disease; autoimmune disease (multiple); end stage renal disease; hyperimmunoglobulin syndrome (multiple); and non-Hodgkin lymphoma (multiple). Orthologous to human CD40 (CD40 molecule). [provided by Alliance of Genome Resources, Apr 2022] |
| Immunogen | KLH conjugated synthetic peptide: human CD40/TNFRSF5. |
| Antigen Species | Human |
| Gene Name | Cd40 |
| Gene ID | |
| Protein Name | Tumor necrosis factor receptor superfamily member 5 |
| Uniprot ID | |
| Biology Area | Innate and adaptive immunity,CD,B Lymphocytic Lineage,Dendritic Cell Lineage |
| Molecular Weight | Theoretical: 30 kDa. Actual: 52 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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