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Synonyms: Serotonin receptor 4, Serotonin 5 HT4 receptor, Htr4a, HTR4, HTR 4, Cardiac 5 HT4 receptor, 5-HTR4(5-hydroxytryptamine(serotonin) receptor 4a), 5HT4R, 5-HT4A, 5-HT4, 5HT4, 5 hydroxytryptamine serotonin receptor 4, 5 hydroxytryptamine receptor 4, 5 hydroxytryptamine 4 receptor, 5 HT4R, 5 HT4, 5 HT 4
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
| Description | Anti-5HT4 Receptor Polyclonal Antibody is a Rabbit antibody targeting 5HT4 Receptor. Anti-5HT4 Receptor Polyclonal Antibody can be used in IF, IHC-Fr, IHC-P, WB. |
| Synonyms | Serotonin receptor 4, Serotonin 5 HT4 receptor, Htr4a, HTR4, HTR 4, Cardiac 5 HT4 receptor, 5-HTR4(5-hydroxytryptamine(serotonin) receptor 4a), 5HT4R, 5-HT4A, 5-HT4, 5HT4, 5 hydroxytryptamine serotonin receptor 4, 5 hydroxytryptamine receptor 4, 5 hydroxytryptamine 4 receptor, 5 HT4R, 5 HT4, 5 HT 4 |
| Ig Type | IgG |
| Reactivity | Mouse,Rat (predicted:Human,Chicken,Cow) |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:200-800 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cell membrane; Multi-pass membrane protein. Endosome. Note=Interaction with SNX27 mediates recruitment to early endosomes, while interaction with SLC9A3R1 and EZR might target the protein to specialized subcellular regions, such as microvilli. |
| Tissue Specificity | soform 5-HT4(A) is expressed in ileum, brain, and atrium, but not in the ventricle. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | This gene is a member of the family of serotonin receptors, which are G protein coupled receptors that stimulate cAMP production in response to serotonin (5-hydroxytryptamine). The gene product is a glycosylated transmembrane protein that functions in both the peripheral and central nervous system to modulate the release of various neurotransmitters. Multiple transcript variants encoding proteins with distinct C-terminal sequences have been described. [provided by RefSeq, May 2010] |
| Immunogen | KLH conjugated synthetic peptide: human 5-HTR4 |
| Antigen Species | Human |
| Gene Name | HTR4 |
| Gene ID | |
| Protein Name | 5-hydroxytryptamine receptor 4 |
| Uniprot ID | |
| Biology Area | Obesity,Serotonin Receptors |
| Function | This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase. |
| Molecular Weight | Theoretical: 43 kDa. Actual: 48 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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