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Anti-CD14 Antibody-APC (5A578) is a APC-conjugated Rabbit antibody targeting CD14. Anti-CD14 Antibody-APC (5A578) can be used in FCM.
Description | Anti-CD14 Antibody-APC (5A578) is a APC-conjugated Rabbit antibody targeting CD14. Anti-CD14 Antibody-APC (5A578) can be used in FCM. |
Ig Type | Monoclonal Rabbit IgG |
Clone | 5A578 |
Reactivity | Human |
Verified Activity | Flow cytometric analysis of Human CD14 expression on human whole blood monocytes. Cells were stained with APC-conjugated anti-Human CD14. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable monocytes. |
Application | FCM |
Recommended Dose | 10 μl/Test, 0.1 mg/ml |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human CD14 (rh CD14; TMPY-02698; NP_000582.1; Met1-Met344) and conjugated with APC under optimum conditions, the unreacted APC was removed. |
Purification | Protein A |
Appearance | Liquid |
Formulation | PBS solution containing 0.5% BSA and 0.03%ProClin300 |
Research Background | The cluster of differentiation (CD) system is commonly used as cell markers in immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. Cluster of differentiation 14 (CD14) is a member of the CD system. It takes its name from its inclusion in the CD molecule surface marker proteins. CD14 exists in two forms: a form anchored into the membrane or a soluble form. CD14 was found expressed in macrophages, neutrophil granulocyte and dendritic cells. The major function is to serve as a co-receptor (along with TLR4 and MD-2) for the bacterial lipopolysaccharide (LPS) and other pathogen-associated molecular patterns. |
Conjucates | APC |
Others Formats | Unconjugated/PerCP/FITC/PE |
Antibody Types Available | 5 |
Immunogen | Recombinant Human CD14 Protein (TMPY-02698) |
Antigen Species | Human |
Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. |
Transport | Shipping with blue ice. |
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