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3-O-beta-D-Glucopyranosylplatycodigenin

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Catalog No. TN1260Cas No. 38337-25-6

3-O-beta-D-Glucopyranosylplatycodigenin is isolated from the roots of Platycodon grandiflorum.

3-O-beta-D-Glucopyranosylplatycodigenin

3-O-beta-D-Glucopyranosylplatycodigenin

🥰Excellent
Purity: 98.76%
Catalog No. TN1260Cas No. 38337-25-6
3-O-beta-D-Glucopyranosylplatycodigenin is isolated from the roots of Platycodon grandiflorum.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$68-In Stock
5 mgPreferential-In Stock
10 mgPreferential-In Stock
1 mL x 10 mM (in DMSO)$288-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:98.76%
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COA HPLC MS HNMR CNMR

Product Introduction

Bioactivity
Description
3-O-beta-D-Glucopyranosylplatycodigenin is isolated from the roots of Platycodon grandiflorum.
Targets&IC50
Antiproliferative:13.36 μM
In vitro
Two new oleanane-type triterpenoids, named platycodonoids A and B (1, 2), together with five known saponins, including platycodin D (3), deapioplatycodin D (4), 3-O-β-D-glucopyranosyl polygalacic acid (5), 3-O-beta-D-Glucopyranosylplatycodigenin (6) and polygalacin D (7), were isolated from the roots of Platycodon grandiflorum. On the basis of spectral data and chemical evidence, the structures of the new compounds were elucidated as 2β,3β,23,24-tetrahydroxy-28-nor-olean-12-en-16-one (1) and 2β,3β,23,24- tetrahydroxy-28-nor-olean-12-en-16-one-3-O-β-D-glucopyranoside (2).
Chemical Properties
Molecular Weight682.84
FormulaC36H58O12
Cas No.38337-25-6
Smiles[H][C@@]1(O[C@H]2[C@@H](O)C[C@@]3(C)[C@@]([H])(CC[C@]4(C)[C@]3([H])CC=C3[C@]5([H])CC(C)(C)CC[C@@]5([C@H](O)C[C@@]43C)C(O)=O)C2(CO)CO)O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O
Relative Density.1.39 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 10 mg/mL (14.64 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 1 mg/mL (1.46 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.4645 mL7.3224 mL14.6447 mL73.2236 mL
5 mM0.2929 mL1.4645 mL2.9289 mL14.6447 mL
10 mM0.1464 mL0.7322 mL1.4645 mL7.3224 mL

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
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Keywords

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