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N-CBZ-Phe-Arg-AMC TFA

🥰Excellent
Catalog No. T76010
Alias Z-FR-AMC TFA

N-CBZ-Phe-Arg-AMC TFA (Z-FR-AMC TFA) is a fluorescent substrate for serine proteases, which releases free AMC upon protease cleavage. Its excitation/emission wavelengths are 380/460 nm, and it can be used to assess the activity of trypsin, plasmin, and cathepsin.

N-CBZ-Phe-Arg-AMC TFA
Other Forms of N-CBZ-Phe-Arg-AMC TFA:

N-CBZ-Phe-Arg-AMC TFA

🥰Excellent
Purity: 99.88%
Catalog No. T76010Alias Z-FR-AMC TFA
N-CBZ-Phe-Arg-AMC TFA (Z-FR-AMC TFA) is a fluorescent substrate for serine proteases, which releases free AMC upon protease cleavage. Its excitation/emission wavelengths are 380/460 nm, and it can be used to assess the activity of trypsin, plasmin, and cathepsin.
Pack SizePriceAvailabilityQuantity
1 mg$46In Stock
5 mg$108In Stock
10 mg$158In Stock
25 mg$322In Stock
50 mg$519In Stock
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Purity:99.88%
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Product Introduction

Bioactivity
Description
N-CBZ-Phe-Arg-AMC TFA (Z-FR-AMC TFA) is a fluorescent substrate for serine proteases, which releases free AMC upon protease cleavage. Its excitation/emission wavelengths are 380/460 nm, and it can be used to assess the activity of trypsin, plasmin, and cathepsin.
SynonymsZ-FR-AMC TFA
Chemical Properties
Molecular Weight726.7
FormulaC35H37F3N6O8
SmilesO=C(N[C@@H](CC1=CC=CC=C1)C(N[C@H](C(NC2=CC=C(C(C)=CC(O3)=O)C3=C2)=O)CCCNC(N)=N)=O)OCC4=CC=CC=C4.O=C(O)C(F)(F)F
ColorWhite
AppearanceSolid
Sequence ShortCBZ-FR-AMC
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 40 mg/mL (55.04 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.3761 mL6.8804 mL13.7608 mL68.8042 mL
5 mM0.2752 mL1.3761 mL2.7522 mL13.7608 mL
10 mM0.1376 mL0.6880 mL1.3761 mL6.8804 mL
20 mM0.0688 mL0.3440 mL0.6880 mL3.4402 mL
50 mM0.0275 mL0.1376 mL0.2752 mL1.3761 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
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