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Anti-SARS-CoV/SARS-CoV-2 Nucleocapsid Antibody (4R223) is a Chimera antibody targeting SARS-CoV/SARS-CoV-2 Nucleocapsid. Anti-SARS-CoV/SARS-CoV-2 Nucleocapsid Antibody (4R223) can be used in ELISA.
Description | Anti-SARS-CoV/SARS-CoV-2 Nucleocapsid Antibody (4R223) is a Chimera antibody targeting SARS-CoV/SARS-CoV-2 Nucleocapsid. Anti-SARS-CoV/SARS-CoV-2 Nucleocapsid Antibody (4R223) can be used in ELISA. |
Ig Type | Monoclonal Rabbit scFv / human IgG1 Fc |
Clone | 4R223 |
Application | ELISA |
Recommended Dose | ELISA: 1:5000-1:10000 |
Antibody Type | Monoclonal |
Host Species | Chimera |
Construction | It is a chimeric monoclonal antibody combining the human IgG1 Fc molecule with rabbit scFv, and the variable region was from rabbit monoclonal antibody (Cat#40143-R004). The chimeric monoclonal antibody was produced using recombinant antibody technology. |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. The coronavirus N protein is required for coronavirus RNA synthesis and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is the most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to the formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. Because of the conservation of the N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool. |
Conjucates | Unconjugated |
Immunogen | Recombinant SARS-CoV Nucleoprotein / NP Protein (TMPY-02870) |
Antigen Species | SARS |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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