IL-18 Protein, Rat, Recombinant

Name: IL-18 Protein, Rat, Recombinant
Brand: TargetMol
SKU: TMPS-00069
Rating: 4.5 (1 reviews)

(Synonyms: interleukin 18, IL-1g, IL1F4, IL-18, IL18, IGIF) Copy Product Info

Synonyms: interleukin 18, IL-1g, IL1F4, IL-18, IL18, IGIF

Catalog No. TMPS-00069 Copy Product Info

IL-18 Protein, Rat, Recombinant is expressed in E. coli. The accession number is P97636-1.

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Pack Size	Price	USA Stock	Global Stock
5 µg	$98	7-10 days	7-10 days
10 µg	$170	7-10 days	7-10 days
20 µg	$297	7-10 days	7-10 days
50 µg	$692	7-10 days	7-10 days
100 µg	$1,180	7-10 days	7-10 days
200 µg	$1,980	7-10 days	7-10 days
500 µg	$4,190	7-10 days	7-10 days
1 mg	$7,230	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Bioactivity

Bioactivity	ED 50 < 2.0 μg/ml resulted in the secretion of 0.15 ng/ml h-IFN-gamma when tested using KG-1 cell line, corresponding to a specific activity of > 500.0 units/mg.
Description	IL-18 Protein, Rat, Recombinant is expressed in E. coli. The accession number is P97636-1.
Species	Rat
Expression System	E. coli
Tag	Tag Free
Accession Number	P97636-1
Construction	His37-Ser194
Protein Purity	> 95% as determined by SDS-PAGE
Endotoxin	< 0.2 EU/μg of protein as determined by the LAL method.
Formulation	Lyophilized after extensive dialysis against 50 mM Tris, 50 mM NaCl, pH 8.0.
Reconstitution	Reconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	interleukin 18, IL-1g, IL1F4, IL-18, IL18, IGIF
Research Background	Interleukin-18 (IL18, also known as interferon-gamma inducing factor or IGIF) is a cytokine that belongs to the IL-1 superfamily and is produced by macrophages and other cells. Its biological activity is pleiotropic and it has been shown to induce interferon-gamma production in KG-1 cells. The combination of this cytokine and IL12 has been shown to inhibit IL4 dependent IgE and IgG1 production, and enhance IgG2a production in B cells.

Chemical Properties

Molecular Weight

~18.4 kDa (Reducing conditions)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	Upon receiving, this product remains stable for up to 6 months at lower than -70°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. For long term storage it is recommended that a carrier protein (example 0.1% BSA) be added. Avoid repeated freeze-thaw cycles.