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Anti-TFPI Polyclonal Antibody
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Catalog No. TMAB-01825
Alias tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor), TFPI1, TFI, LACI, EPI
Anti-TFPI Polyclonal Antibody is a Rabbit antibody targeting TFPI. Anti-TFPI Polyclonal Antibody can be used in WB.
Anti-TFPI Polyclonal Antibody
Anti-TFPI Polyclonal Antibody
😃Good
Catalog No. TMAB-01825Alias tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor), TFPI1, TFI, LACI, EPI
Anti-TFPI Polyclonal Antibody is a Rabbit antibody targeting TFPI. Anti-TFPI Polyclonal Antibody can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-TFPI Polyclonal Antibody is a Rabbit antibody targeting TFPI. Anti-TFPI Polyclonal Antibody can be used in WB. |
| Synonyms | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor), TFPI1, TFI, LACI, EPI |
| Ig Type | IgG |
| Reactivity | Mouse,Rat (predicted:Human,Pig,Cow,Horse,Rabbit) |
| Verified Activity | Sample: Heart (Mouse) Lysate at 40 μg Lung (Rat) Lysate at 40 μg Primary: Anti-TFPI (TMAB-01825) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 32 kDa Observed band size: 52 kDa  |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Isoform Alpha: Secreted. Isoform Beta: Microsome membrane; Lipid-anchor, GPI-anchor. |
| Tissue Specificity | Mostly in endothelial cells. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | TFPI is a protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. TFPI inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop. TFPI is glycosylated and predominantly found in the vascular endothelium and plasma in both free forms and complexed with plasma lipoproteins. |
| Immunogen | KLH conjugated synthetic peptide: human TFPI |
| Antigen Species | Human |
| Gene Name | TFPI |
| Gene ID | |
| Protein Name | Tissue factor pathway inhibitor |
| Uniprot ID | |
| Biology Area | Platelets,Extrinsic |
| Function | Inhibits factor X (X(a)) directly and, in a Xa-dependent way, inhibits VIIa/tissue factor activity, presumably by forming a quaternary Xa/LACI/VIIa/TF complex. It possesses an antithrombotic action and also the ability to associate with lipoproteins in plasma. |
| Molecular Weight | Theoretical: 32 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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