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Anti-Marapsin Antibody (8L443) (Synonyms: UNQ1884/PRO4327, protease, serine 27, MPN, CAPH2)
Catalog No. TMAY-02243 Copy Product Info
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Anti-Marapsin Antibody (8L443) is a Rabbit antibody targeting Marapsin. Anti-Marapsin Antibody (8L443) can be used in IP,WB.
Anti-Marapsin Antibody (8L443)
Copy Product Info🥰Excellent
Catalog No. TMAY-02243
Synonyms UNQ1884/PRO4327, protease, serine 27, MPN, CAPH2
Anti-Marapsin Antibody (8L443) is a Rabbit antibody targeting Marapsin. Anti-Marapsin Antibody (8L443) can be used in IP,WB.
Anti-Marapsin Antibody
(8L443)
(8L443)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 100 μL | $269 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-Marapsin Antibody (8L443) is a Rabbit antibody targeting Marapsin. Anti-Marapsin Antibody (8L443) can be used in IP,WB. |
| Synonyms | UNQ1884/PRO4327, protease, serine 27, MPN, CAPH2 |
| Ig Type | Rabbit IgG |
| Clone | 8L443 |
| Reactivity | Human |
| Specificity | Human Marapsin |
| Verified Activity | 1. Anti-PRSS27 rabbit monoclonal antibody at 1:500 dilution. -Lane A: K562 Whole Cell lysate. -Lysates/proteins at 30 μg per lane. -Secondary -Goat Anti-Rabbit IgG H&L (Dylight800) at 1/10000 dilution. -Developed using the Odyssey technique. -Performed under reducing conditions. -Predicted band size:32 kDa. -Observed band size:32 kDa. 2. PRSS27 was immunoprecipitated using: -Lane A:0.5 mg K562 Whole Cell Lysate. -2 µL anti-PRSS27 rabbit monoclonal antibody and 15 μl of 50 % Protein G agarose. -Primary antibody: -Anti-PRSS27 rabbit monoclonal antibody, at 1:200 dilution. -Secondary antibody: -Dylight 800-labeled antibody to rabbit IgG (H+L), at 1:5000 dilution. -Developed using the odyssey technique. -Performed under reducing conditions. -Predicted band size: 32 kDa. -Observed band size: 32 kDa |
| Application | |
| Recommended Dose | WB: 1:500-1:2000; IP: 4-6 μL/mg of lysate |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human Pancreasin / Marapsin / PRSS27 (rh Pancreasin / Marapsin / PRSS27; TMPY-02117; Q9BQR3; Met1-Lys290). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | The name "Pancreasin" because it is transcribed strongly in the pancreas. This secreted, tryptic serine protease, also known as Marapsin or PRSS27 (Protease, serine, 27), is a member of the peptidase S1 family. Pancreasin is inhibited by benzamidine and leupeptin but resists several classic inhibitors of trypsin. Marapsin was constitutively expressed in nonkeratinizing stratified squamous epithelia of human esophagus, tonsil, cervix, larynx, and cornea. In fact, marapsin was the second most strongly up-regulated protease in psoriatic lesions, where expression was localized to the upper region of the hyperplastic epidermis. Similarly, in the hyperproliferative epithelium of regenerating murine skin wounds, marapsin localized to the suprabasal layers, where keratinocytes undergo squamous differentiation. Marapsin's restricted expression, localization, and cytokine-inducible expression suggest a role in the terminal differentiation of keratinocytes in hyperproliferating squamous epithelia. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human Pancreasin / Marapsin / PRSS27 protein (TMPY-02117) |
| Antigen Species | Human |
| Biology Area | Serine Proteases and Regulators |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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