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[cPP1-7,NPY19-23,Ala31,Aib32,Gln34]-hPancreatic polypeptide TFA

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Catalog No. T75913

[cPP1-7,NPY19-23,Ala31,Aib32,Gln34]-hPancreatic Polypeptide is a potent and selective neuropeptide Y Y5 receptor agonist, exhibiting a binding affinity with an IC50 of 0.24 nM for the hY5 receptor, and significantly stimulates food intake [1].

[cPP1-7,NPY19-23,Ala31,Aib32,Gln34]-hPancreatic polypeptide TFA
Other Forms of [cPP1-7,NPY19-23,Ala31,Aib32,Gln34]-hPancreatic polypeptide TFA:
[cPP1-7,NPY19-23,Ala31,Aib32,Gln34]-hPancreatic PolypeptideTP1963313988-89-5
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[cPP1-7,NPY19-23,Ala31,Aib32,Gln34]-hPancreatic polypeptide TFA

😃Good
Catalog No. T75913
[cPP1-7,NPY19-23,Ala31,Aib32,Gln34]-hPancreatic Polypeptide is a potent and selective neuropeptide Y Y5 receptor agonist, exhibiting a binding affinity with an IC50 of 0.24 nM for the hY5 receptor, and significantly stimulates food intake [1].
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Product Introduction

Bioactivity
Description
[cPP1-7,NPY19-23,Ala31,Aib32,Gln34]-hPancreatic Polypeptide is a potent and selective neuropeptide Y Y5 receptor agonist, exhibiting a binding affinity with an IC50 of 0.24 nM for the hY5 receptor, and significantly stimulates food intake [1].
Targets&IC50
Y2 receptor (human):>500 nM, Y4 receptor (human):51 nM, Y5 receptor (human):0.24 nM, Y1 receptor (human):530 nM
Chemical Properties
Molecular Weight4321.68
FormulaC185H282F3N57O56S2
Sequence ShortGPSQPTYPGDNATPEQMARYYSALRRYINMA{Aib}RQRY-NH2
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
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