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Monotropein

🥰Excellent
Catalog No. T6S1579Cas No. 5945-50-6
Alias Monotropeine

1. Monotropein (Monotropeine) has antinociceptive action. 2. Monotropein has anti-apoptosis and anti-catabolic activity in chondrocytes. 3. Monotropein has anti-inflammatory action by inhibition of the expressions of inflammatory mediators via NF-κB inactivation, and support its possible therapeutic role in colitis. 4. Monotrope ininhibit the expressions of inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2), tumor necrosis factor-α (TNF-α), and interleukin-1β (IL-1β) mRNA in LPS-induced RAW 264.7 macrophages.

Monotropein

Monotropein

🥰Excellent
Purity: 99.66%
Catalog No. T6S1579Alias MonotropeineCas No. 5945-50-6
1. Monotropein (Monotropeine) has antinociceptive action. 2. Monotropein has anti-apoptosis and anti-catabolic activity in chondrocytes. 3. Monotropein has anti-inflammatory action by inhibition of the expressions of inflammatory mediators via NF-κB inactivation, and support its possible therapeutic role in colitis. 4. Monotrope ininhibit the expressions of inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2), tumor necrosis factor-α (TNF-α), and interleukin-1β (IL-1β) mRNA in LPS-induced RAW 264.7 macrophages.
Pack SizePriceAvailabilityQuantity
2 mg$32In Stock
5 mg$50In Stock
10 mg$85In Stock
25 mg$167In Stock
50 mg$246In Stock
100 mg$363In Stock
200 mg$539In Stock
1 mL x 10 mM (in DMSO)$59In Stock
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Purity:99.66%
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Product Introduction

Bioactivity
Description
1. Monotropein (Monotropeine) has antinociceptive action. 2. Monotropein has anti-apoptosis and anti-catabolic activity in chondrocytes. 3. Monotropein has anti-inflammatory action by inhibition of the expressions of inflammatory mediators via NF-κB inactivation, and support its possible therapeutic role in colitis. 4. Monotrope ininhibit the expressions of inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2), tumor necrosis factor-α (TNF-α), and interleukin-1β (IL-1β) mRNA in LPS-induced RAW 264.7 macrophages.
SynonymsMonotropeine
Chemical Properties
Molecular Weight390.34
FormulaC16H22O11
Cas No.5945-50-6
Smiles[H][C@]12C=C[C@](O)(CO)[C@@]1([H])[C@H](O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)OC=C2C(O)=O
Relative Density.1.73 g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
Ethanol: Insoluble
DMSO: 71 mg/mL (181.89 mM), Sonication is recommended.
Pyridine, Methanol, etc.: Soluble
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.5619 mL12.8093 mL25.6187 mL128.0935 mL
5 mM0.5124 mL2.5619 mL5.1237 mL25.6187 mL
10 mM0.2562 mL1.2809 mL2.5619 mL12.8093 mL
20 mM0.1281 mL0.6405 mL1.2809 mL6.4047 mL
50 mM0.0512 mL0.2562 mL0.5124 mL2.5619 mL
100 mM0.0256 mL0.1281 mL0.2562 mL1.2809 mL

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Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
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Keywords

MonotropeinInhibitorinhibit
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