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TrkA Protein, Human, Recombinant (aa 33-417, His)

TargetMol | SPR
Catalog No. TMPK-00774 Copy Product Info
TrkA, a tyrosine kinase receptor, is an essential component of the nerve growth factor (NGF) response pathway. The binding of NGF to the receptor induces receptor autophosphorylation and activation of intracellular signaling pathways, resulting in diverse biological effects.

TrkA Protein, Human, Recombinant (aa 33-417, His)

Catalog No. TMPK-00774
Copy Product Info
TargetMol | SPR

TrkA, a tyrosine kinase receptor, is an essential component of the nerve growth factor (NGF) response pathway. The binding of NGF to the receptor induces receptor autophosphorylation and activation of intracellular signaling pathways, resulting in diverse biological effects.

TrkA Protein, Human, Recombinant (aa 33-417, His)
Pack SizePriceUSA StockGlobal StockQuantity
5 μg$517-10 days7-10 days
10 μg$807-10 days7-10 days
20 μg$1297-10 days7-10 days
50 μg$2487-10 days7-10 days
100 μg$4187-10 days7-10 days
200 μg$7577-10 days7-10 days
500 μg$1,6707-10 days7-10 days
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For In stock only · Estimated delivery:USA Stock (1-2 days) Global Stock (5-7 days)
For research use only—not for human use. No sales to individuals. Use as intended only.
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Batch Information

Product Information

Biological Activity
Immobilized Human Beta-NGF, No Tag at 1 μg/mL (100 μL/well) on the plate. Dose response curve for Human TrkA, His Tag with the EC50 of 0.21 μg/mL determined by ELISA.(QC Test)
Description
TrkA, a tyrosine kinase receptor, is an essential component of the nerve growth factor (NGF) response pathway. The binding of NGF to the receptor induces receptor autophosphorylation and activation of intracellular signaling pathways, resulting in diverse biological effects.
Species
Human
Expression System
HEK293 Cells
TagC-His
Accession NumberP04629-2
Synonyms
TrkA-I,TrkAI,TrkA I,Trk-A,TRKA,TRK,NTRK1,MTC
Construction
Ala33-Gly417
Protein Purity
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Molecular Weight43.00 kDa (predicted). Due to glycosylation, the protein migrates to 70-100 kDa based on Tris-Bis PAGE result.
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationLyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
Reconstitution
Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Stability & Storage
It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Research Background
TrkA, a tyrosine kinase receptor, is an essential component of the nerve growth factor (NGF) response pathway. The binding of NGF to the receptor induces receptor autophosphorylation and activation of intracellular signaling pathways, resulting in diverse biological effects.

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