Powder: -20°C for 3 years | In solvent: -80°C for 1 year
SNIPER(TACC3)-11 is a potent degrader of the FGFR3-TACC3 protein, effectively diminishing its levels and inhibiting the proliferation of cancer cells positive for FGFR3-TACC3 [1].
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Description | SNIPER(TACC3)-11 is a potent degrader of the FGFR3-TACC3 protein, effectively diminishing its levels and inhibiting the proliferation of cancer cells positive for FGFR3-TACC3 [1]. |
In vitro | SNIPER(TACC3)-11 (compound 5a), at concentrations ranging from 0.3 to 3 µM over six hours, diminishes the levels of FGFR3-TACC3 [1]. Additionally, a 72-hour exposure to SNIPER(TACC3)-11 at the same concentration range specifically impedes the proliferation of RT4 cells at 3 µM, while exhibiting no inhibitory effects on HeLa cell growth [1]. |
Molecular Weight | 995.26 |
Formula | C51H66N10O7S2 |
CAS No. | 2906151-68-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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SNIPER(TACC3)-11 2906151-68-4 inhibitor inhibit