HER2/ERBB2 Protein, Human, Recombinant (hFc)

Name: HER2/ERBB2 Protein, Human, Recombinant (hFc)
Brand: TargetMol
SKU: TMPY-00745
Price: 68 USD
Availability: InStock
Rating: 5 (10 reviews)

(Synonyms: TKR1, NGL, NEU, MLN19, MLN 19, HERV-W-ENV, HERVWENV, HERVW, HERV-7q, HERV7Q, HER-2/neu, HER-2, HER2, ERVWE1, erb-b2 receptor tyrosine kinase 2, ENVW, ENV, EGFR2, CD340) Copy Product Info

Synonyms: TKR1, NGL, NEU, MLN19, MLN 19, HERV-W-ENV, HERVWENV, HERVW, HERV-7q, HERV7Q, HER-2/neu, HER-2, HER2, ERVWE1, erb-b2 receptor tyrosine kinase 2, ENVW, ENV, EGFR2, CD340

Catalog No. TMPY-00745 Copy Product Info

HER2/ERBB2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 96.1 kDa and the accession number is P04626-1.

Pack Size	Price	USA Stock	Global Stock
5 µg	$68	-	In Stock
10 µg	$109	-	In Stock
20 µg	$172	-	In Stock
50 µg	$343	7-10 days	7-10 days
100 µg	$682	-	In Stock
200 µg	$980	7-10 days	7-10 days
500 µg	$1,980	7-10 days	7-10 days
1 mg	$3,970	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:> 95% as determined by Bis-Tris PAGE > 95% as determined by HPLC

Appearance:Lyophilized powder

Color:White

Resource Download

COA User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Immobilized Human Her2, hFc Tag at 5 μg/ml (100 μl/well) on the plate. Dose response curve for Biotinylated Anti-Her2 Antibody , hFc Tag with the EC50 of 0.26 μg/ml determined by ELISA.
Description	HER2/ERBB2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 96.1 kDa and the accession number is P04626-1.
Species	Human
Expression System	HEK293 Cells
Tag	C-hFc
Accession Number	P04626-1
Construction	Thr23-Thr652
Protein Purity	> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	TKR1, NGL, NEU, MLN19, MLN 19, HERV-W-ENV, HERVWENV, HERVW, HERV-7q, HERV7Q, HER-2/neu, HER-2, HER2, ERVWE1, erb-b2 receptor tyrosine kinase 2, ENVW, ENV, EGFR2, CD340
Research Background	ErbB2, also called Neu and Her2 (human epidermal growth factor receptor 2), is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors. ErbB family members serve as receptors for the epidermal growth factor (EGF) family of growth factors.Upon ERBB2 activation, the MEMO1-RHOA-DIAPH1 signaling pathway elicits the phosphorylation and thus the inhibition of GSK3B at cell membrane. This prevents the phosphorylation of APC and CLASP2, allowing its association with the cell membrane.

Chemical Properties

Molecular Weight

96.1 kDa (Predicted); 100-120 kDa (Due to glycosylation)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.