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Anti-MAPT Antibody (2F162) is an antibody targeting MAPT. Anti-MAPT Antibody (2F162) can be used in ELISA.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $208 | 7-10 days | |
100 μL | $349 | 7-10 days |
Description | Antibody Type: Recombinant Monoclonal Application: ELISA Reactivity: Mouse, Macaca mulatta |
Alias | TAU and MAPT, Paired helical filament-tau, Neurofibrillary tangle protein, MTBT1, Microtubule-associated protein tau, MAPTL |
Ig Type | Human IgG4(S228P) |
Clone | 2F162 |
Reactivity | Mouse, Macaca mulatta |
Verified Activity | 1. The Binding Activity of Mapt with Anti-MAPT recombinant antibody Activity: Measured by its binding ability in a functional ELISA. Immobilized Mouse Mapt at 2 μg/ml can bind Anti-MAPT recombinant antibody, the EC50 is 436.1-518.6 ng/ml. 2. The Binding Activity of MAPT with Anti-MAPT recombinant antibody Activity: Measured by its binding ability in a functional ELISA. Immobilized Macaca mulatta MAPT at 2 μg/ml can bind Anti-MAPT recombinant antibody, the EC50 is 2.464-3.979 ng/ml. |
Application | ELISA |
Antibody Type | Monoclonal |
Subcellular Localization | Cytoplasm, cytosol. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Cell projection, axon. Cell projection, dendrite. Secreted. |
Construction | Recombinant Antibody |
Purification | Affinity-chromatography |
Appearance | Liquid |
Formulation | Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. |
Research Background | Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization. |
Conjucates | Unconjugated |
Immunogen | Recombinant Protein: Human MAPT Protein |
Antigen Species | Human |
Gene ID | 4137 |
Uniprot ID | |
Biology Area | Immunology |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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