Anti-Fas Ligand Polyclonal Antibody

Name: Anti-Fas Ligand Polyclonal Antibody
Brand: TargetMol
SKU: TMAB-00655
Rating: 4.5 (1 reviews)

(Synonyms: TNLG1A, TNFSF6, FASLG, FASL, Fas ligand, CD95-L, CD95L, CD178, APTL, APT1LG1, ALPS1B) Copy Product Info

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Synonyms: TNLG1A, TNFSF6, FASLG, FASL, Fas ligand, CD95-L, CD95L, CD178, APTL, APT1LG1, ALPS1B

Catalog No. TMAB-00655 Copy Product Info

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Anti-Fas Ligand Polyclonal Antibody is a Rabbit antibody targeting Fas Ligand. Anti-Fas Ligand Polyclonal Antibody can be used in FCM,IF,IHC-Fr,IHC-P,WB.

Anti-Fas Ligand Polyclonal Antibody

Pack Size	Price	USA Stock	Global Stock
50 μL	$222	7-10 days	7-10 days
100 μL	$372	7-10 days	7-10 days
200 μL	$528	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Instruction Manual of Detection Antibody

Product Introduction

Bioactivity

Description	Anti-Fas Ligand Polyclonal Antibody is a Rabbit antibody targeting Fas Ligand. Anti-Fas Ligand Polyclonal Antibody can be used in FCM,IF,IHC-Fr,IHC-P,WB.
Synonyms	TNLG1A, TNFSF6, FASLG, FASL, Fas ligand, CD95-L, CD95L, CD178, APTL, APT1LG1, ALPS1B
Ig Type	IgG
Reactivity	Human,Mouse,Rat (predicted:Cow)

Application	FCM IF IHC-Fr IHC-P WB
Recommended Dose	WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; FCM: 1μg/Test
Antibody Type	Polyclonal
Host Species	Rabbit
Subcellular Localization	Cell membrane; Single-pass type II membrane protein. Secreted. Cytoplasmic vesicle lumen. Lysosome lumen. Note=May be released into the extracellular fluid, probably by cleavage form the cell surface. Is internalized into multivesicular bodies of secretory lysosomes after phosphorylation by FGR and monoubiquitination.
Construction	Polyclonal Antibody
Purification	Protein A purified
Appearance	Liquid
Formulation	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration	1 mg/mL
Research Background	This gene is a member of the tumor necrosis factor superfamily. The primary function of the encoded transmembrane protein is the induction of apoptosis triggered by binding to FAS. The FAS/FASLG signaling pathway is essential for immune system regulation, including activation-induced cell death (AICD) of T cells and cytotoxic T lymphocyte induced cell death. It has also been implicated in the progression of several cancers. Defects in this gene may be related to some cases of systemic lupus erythematosus (SLE). Alternatively spliced transcript variants have been described. [provided by RefSeq, Nov 2014]

Antigen Details

Immunogen	KLH conjugated synthetic peptide: human Fas Ligand
Antigen Species	Human
Gene Name	FASLG
Gene ID	356
Protein Name	Tumor necrosis factor ligand superfamily member 6
Uniprot ID	P48023
Function	Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells. May be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. Binding to the decoy receptor TNFRSF6B/DcR3 modulates its effects.