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8-Epiloganin (8-epi-Loganin) is a compound isolated from Pedicularis lasiophrys with anti-inflammatory activity. It inhibits the release of pro-inflammatory cytokines induced by LPS.

| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $195 | - | In Stock | |
| 5 mg | $483 | - | In Stock | |
| 10 mg | $692 | - | In Stock | |
| 25 mg | $1,080 | - | In Stock | |
| 50 mg | $1,490 | - | In Stock |
| Description | 8-Epiloganin (8-epi-Loganin) is a compound isolated from Pedicularis lasiophrys with anti-inflammatory activity. It inhibits the release of pro-inflammatory cytokines induced by LPS. |
| In vitro | 8-Epiloganin(25-200 μM,12h) inhibited the expression of COX-2 and iNOS in RAW264.7 macrophages induced by LPS, thereby inhibiting the production of COX-2-derived PGE2 and iNOS derived NO. [1] |
| In vivo | 8-Epiloganin showed anti-fatigue activity in mice. [2] |
| Synonyms | 8-epi-Loganin |
| Molecular Weight | 390.38 |
| Formula | C17H26O10 |
| Cas No. | 79172-04-6 |
| Smiles | O([C@H]1[C@]2([C@@](C(C(OC)=O)=CO1)(C[C@H](O)[C@H]2C)[H])[H])[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O |
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
Dissolve 2 mg of the compound in 100 μL DMSO
to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO
stock solution to 400 μL PEG300
and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O
and mix thoroughly until a homogeneous solution is obtained.
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