Powder: -20°C for 3 years | In solvent: -80°C for 1 year
TRPC6-PAM-C20 is a selective TRPC6 positive allosteric modulator. TRPC6-PAM-C20 induces transient increase in intracellular Ca2+ in HEK cells expressing TRPC6 with an EC50 of 2.37 μM. TRPC6-PAM-C20 enhances OAG-induced platelet aggregation.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 178.00 | |
5 mg | In stock | $ 455.00 | |
10 mg | In stock | $ 672.00 | |
25 mg | In stock | $ 1,060.00 | |
50 mg | In stock | $ 1,430.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 490.00 |
Description | TRPC6-PAM-C20 is a selective TRPC6 positive allosteric modulator. TRPC6-PAM-C20 induces transient increase in intracellular Ca2+ in HEK cells expressing TRPC6 with an EC50 of 2.37 μM. TRPC6-PAM-C20 enhances OAG-induced platelet aggregation. |
Targets&IC50 | TRPC6 (HEK293 cells):2.37 μM (EC50) |
Synonyms | TRPC6-PAM-C20, 3-(6,7-Dimethoxy-3,3-dimethyl-3,4-dihydro-isoquinolin-1-yl)-chromen-2-one |
Molecular Weight | 363.41 |
Formula | C22H21NO4 |
CAS No. | 667427-75-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 90 mg/mL (247.65 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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TRPC6-PAM-C20 667427-75-0 Membrane transporter/Ion channel TRP/TRPV Channel 3-(6,7-Dimethoxy-3,3-dimethyl-3,4-dihydro-isoquinolin-1-yl)-chromen-2-one inhibitor inhibit