Contact UsQuotation
Shopping Cart
Remove All
  • TargetMol
    Your shopping cart is currently empty
Proceed to checkoutContinue shopping
TOPBioactivityChemical infoStorage&SolubilityCalculator

4,4'-DIMETHOXYBENZIL

Copy Product Info
🥰Excellent
Catalog No. T5943Cas No. 1226-42-2
Alias p-Anisil

4,4'-Dimethoxybenzil (p-Anisil) is a human intestinal carboxyl esterase (hiCE) inhibitor( Ki : 70 nM).

4,4'-DIMETHOXYBENZIL

4,4'-DIMETHOXYBENZIL

Copy Product Info
🥰Excellent
Purity: 99.04%
Catalog No. T5943Alias p-AnisilCas No. 1226-42-2
4,4'-Dimethoxybenzil (p-Anisil) is a human intestinal carboxyl esterase (hiCE) inhibitor( Ki : 70 nM).
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 g$29In StockIn Stock
1 mL x 10 mM (in DMSO)$29In StockIn Stock
Add to Cart
Add to Quotation
In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Questions
TargetMol
View More

Batch Information

Select Batch
Purity:99.04%
Appearance:Solid
Color:White
Contact us for more batch information

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity
Description
4,4'-Dimethoxybenzil (p-Anisil) is a human intestinal carboxyl esterase (hiCE) inhibitor( Ki : 70 nM).
Targets&IC50
Carboxyl esterase (human intestine):70 nM(Ki)
In vitro
HiCE inhibitors (4,4'-Dimethoxybenzil) mitigate irinotecan-induced diarrhea, thereby enhancing the anticancer efficacy of irinotecan.
Synonymsp-Anisil
Chemical Properties
Molecular Weight270.28
FormulaC16H14O4
Cas No.1226-42-2
SmilesC(C(=O)C1=CC=C(OC)C=C1)(=O)C2=CC=C(OC)C=C2
Relative Density.1.2117 g/cm3 (Estimated)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 6.25 mg/mL (23.12 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.6999 mL18.4993 mL36.9987 mL184.9933 mL
5 mM0.7400 mL3.6999 mL7.3997 mL36.9987 mL
10 mM0.3700 mL1.8499 mL3.6999 mL18.4993 mL
20 mM0.1850 mL0.9250 mL1.8499 mL9.2497 mL

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Inhibitorinhibithuman intestinal carboxyl esterase (hiCE)4,4'-DIMETHOXYBENZIL4,4'DIMETHOXYBENZIL4,4' DIMETHOXYBENZIL
Related Tags: buy 4,4'-DIMETHOXYBENZIL | purchase 4,4'-DIMETHOXYBENZIL | 4,4'-DIMETHOXYBENZIL cost | order 4,4'-DIMETHOXYBENZIL | 4,4'-DIMETHOXYBENZIL chemical structure | 4,4'-DIMETHOXYBENZIL in vitro | 4,4'-DIMETHOXYBENZIL formula | 4,4'-DIMETHOXYBENZIL molecular weight
TargetMol | Logo

Copyright © 2015-2026 TargetMol Chemicals Inc. All Rights Reserved.