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Anti-KRT7 Antibody (7A324)

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Catalog No. TMAY-00119

Anti-KRT7 Antibody (7A324) is a Mouse antibody targeting KRT7. Anti-KRT7 Antibody (7A324) can be used in IHC-P.

Anti-KRT7 Antibody (7A324)

Anti-KRT7 Antibody (7A324)

😃Good
Catalog No. TMAY-00119
Anti-KRT7 Antibody (7A324) is a Mouse antibody targeting KRT7. Anti-KRT7 Antibody (7A324) can be used in IHC-P.
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100 μL$198 7-10 days
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Product Introduction

Bioactivity
Description
Anti-KRT7 Antibody (7A324) is a Mouse antibody targeting KRT7. Anti-KRT7 Antibody (7A324) can be used in IHC-P.
Ig Type
Monoclonal Mouse IgG3
Clone
7A324
Reactivity
Human
Verified Activity
1. Immunochemical staining of human KRT7 in human breast carcinoma with mouse monoclonal antibody (1:50, formalin-fixed paraffin embedded sections).

2. Immunochemical staining of human KRT7 in human gastric cancer with mouse monoclonal antibody (1:50, formalin-fixed paraffin embedded sections).
Application
IHC-P
Recommended Dose
IHC-P: 1:50-1:200
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with a synthetic peptide corresponding to the center region of the Human KRT7 / Cytokeratin-7. The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS with 10% Trehalose, 0.1% BSA, pH 7.0
Research BackgroundKRT7 (Keratin 7) is a Protein Coding gene. The protein encoded by this gene is a member of the keratin gene family. One AS, designated Homo sapiens keratin 7 (KRT7-AS), was selected due to its marked upregulation and concordant expression with its cognate sense counterpart, KRT7, in GC tissues and cell lines. KRT7-AS formed an RNA-RNA hybrid with KRT7 and controlled KRT7 expression at both the mRNA and the post-transcriptional levels. Moreover, forced overexpression of the KRT7-overlapping region (OL) of KRT7-AS (but not its non-KRT7-OL portions) increased keratin 7 protein levels in cells. Finally, forced overexpression of full-length KRT7-AS or OL KRT7-AS (but not its non-KRT7-OL regions) promoted GC cell proliferation and migration.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
A synthetic peptide corresponding to the center region of the Human KRT7 /  Cytokeratin-7
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

Sci Citations

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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