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Anti-KRT7 Antibody (7A324)
😃Good
Catalog No. TMAY-00119
Anti-KRT7 Antibody (7A324) is a Mouse antibody targeting KRT7. Anti-KRT7 Antibody (7A324) can be used in IHC-P.
Anti-KRT7 Antibody (7A324)
Anti-KRT7 Antibody (7A324)
😃Good
Catalog No. TMAY-00119
Anti-KRT7 Antibody (7A324) is a Mouse antibody targeting KRT7. Anti-KRT7 Antibody (7A324) can be used in IHC-P.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 100 μL | $198 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-KRT7 Antibody (7A324) is a Mouse antibody targeting KRT7. Anti-KRT7 Antibody (7A324) can be used in IHC-P. |
| Ig Type | Mouse IgG3 |
| Clone | 7A324 |
| Reactivity | Human |
| Specificity | Human Cytokeratin 7/KRT7 |
| Verified Activity | 1. Immunochemical staining of human KRT7 in human breast carcinoma with mouse monoclonal antibody (1:50, formalin-fixed paraffin embedded sections). 2. Immunochemical staining of human KRT7 in human gastric cancer with mouse monoclonal antibody (1:50, formalin-fixed paraffin embedded sections). |
| Application | |
| Recommended Dose | IHC-P: 1:50-1:200 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with a synthetic peptide corresponding to the center region of the Human KRT7 / Cytokeratin-7. The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS with 10% Trehalose, 0.1% BSA, pH 7.0 |
| Research Background | KRT7 (Keratin 7) is a Protein Coding gene. The protein encoded by this gene is a member of the keratin gene family. One AS, designated Homo sapiens keratin 7 (KRT7-AS), was selected due to its marked upregulation and concordant expression with its cognate sense counterpart, KRT7, in GC tissues and cell lines. KRT7-AS formed an RNA-RNA hybrid with KRT7 and controlled KRT7 expression at both the mRNA and the post-transcriptional levels. Moreover, forced overexpression of the KRT7-overlapping region (OL) of KRT7-AS (but not its non-KRT7-OL portions) increased keratin 7 protein levels in cells. Finally, forced overexpression of full-length KRT7-AS or OL KRT7-AS (but not its non-KRT7-OL regions) promoted GC cell proliferation and migration. |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide: center region of the Human KRT7 / Cytokeratin-7 |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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