Powder: -20°C for 3 years | In solvent: -80°C for 1 year
5-hydroxytryptophan (NSC-92523) is the immediate precursor in the biosynthesis of SEROTONIN from tryptophan. It is used as an antiepileptic and antidepressant.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
20 mg | In stock | $ 50.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 50.00 |
Description | 5-hydroxytryptophan (NSC-92523) is the immediate precursor in the biosynthesis of SEROTONIN from tryptophan. It is used as an antiepileptic and antidepressant. |
In vitro | 5-Hydroxytryptophan exhibits toxicity in mice with an LD50 of 1800 mg/kg. In rats, it demonstrates effects at a dosage of 300 mg/kg when administered intragastrically (i.g.). |
In vivo | 5-Hydroxytryptophan is an intermediate in the biosynthesis of serotonin from the essential amino acid L-tryptophan, which can easily cross the blood-brain barrier and effectively increase the synthesis of serotonin within the central nervous system. It has been shown to improve conditions such as depression, chronic headaches, and insomnia. |
Source |
Synonyms | NSC-92523 |
Molecular Weight | 220.22 |
Formula | C11H12N2O3 |
CAS No. | 56-69-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 41 mg/mL (186.2 mM)
Ethanol: < 1 mg/mL (insoluble or slightly soluble)
H2O: 4 mg/mL (18.16 mM)
You can also refer to dose conversion for different animals. More
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5-hydroxytryptophan 56-69-9 Metabolism Others Endogenous Metabolite 5-HTP NSC 92523 5-Hydroxytryptophan NSC92523 5hydroxytryptophan 5 hydroxytryptophan NSC-92523 inhibit Inhibitor inhibitor