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Calcium Ionophore I (Synonyms: ETH 1001)

Name: Calcium Ionophore I
Brand: TargetMol
SKU: T21663
Rating: 4.5 (1 reviews)

Catalog No. T21663 Copy Product Info

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Calcium Ionophore I (ETH 1001) is a highly selective Ca2+ ionophore designed for biological membranes. It functions by forming stable complexes with calcium ions, facilitating their transport across lipid bilayers. This compound is extensively utilized in the development of Ca2+-selective microelectrodes, which enable precise quantitative measurements of intracellular resting Ca2+ activities and the monitoring of slow kinetic calcium fluctuations. Its high selectivity makes it an indispensable tool for investigating ion homeostasis and signaling in various cellular models.

Calcium Ionophore I

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Catalog No. T21663

Synonyms ETH 1001

Cas No. 58801-34-6

Pack Size	Price	USA Stock	Global Stock
5 mg	$232	35 days	35 days
10 mg	$429	35 days	35 days
25 mg	$978	35 days	35 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Appearance:Liquid

Color:Transparent

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Product Introduction

Bioactivity

Description	Calcium Ionophore I (ETH 1001) is a highly selective Ca2+ ionophore designed for biological membranes. It functions by forming stable complexes with calcium ions, facilitating their transport across lipid bilayers. This compound is extensively utilized in the development of Ca2+-selective microelectrodes, which enable precise quantitative measurements of intracellular resting Ca2+ activities and the monitoring of slow kinetic calcium fluctuations. Its high selectivity makes it an indispensable tool for investigating ion homeostasis and signaling in various cellular models.
In vitro	Calcium Ionophore I (ETH 1001) selectively transports Ca²⁺ across biological membranes without permeating Mg²⁺, exhibiting exceptional divalent cation discrimination. It is widely used in Ca²⁺-selective microelectrodes for high spatiotemporal resolution monitoring of intracellular Ca²⁺ dynamics [1][2].
Synonyms	ETH 1001

Chemical Properties

Molecular Weight	685
Formula	C₃₈H₇₂N₂O₈
Cas No.	58801-34-6
Smiles	[C@@H]([C@H](OCC(N(CCCCCCCCCCCC(OCC)=O)C)=O)C)(OCC(N(CCCCCCCCCCCC(OCC)=O)C)=O)C
Relative Density.	1g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc