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UBE2D1 Protein, Human, Recombinant (His)
(Synonyms: ubiquitin-conjugating enzyme E2D 1, UBCH5A, UBCH5, UBC4/5, SFT, E2(17)KB1) Copy Product InfoSynonyms: ubiquitin-conjugating enzyme E2D 1, UBCH5A, UBCH5, UBC4/5, SFT, E2(17)KB1
Catalog No. TMPY-02426 Copy Product Info
Ubiquitin-conjugating enzyme E2 D1 (UBE2D1), a member of human E2 ubiquitin-conjugating enzymes, is closely related to SFT, which is short for stimulator of iron (Fe) transport. In other words, UbcH5A is significantly up-regulated in the liver of iron-overloaded patients with hereditary hemochromatosis, as previously published for SFT. Moreover, a complex of UBE2D1 is critical in maintaining KRAS protein stability and propose that targeting such complex may be a unique strategy to degrade mutant KRAS to kill cancer cells.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 μg | $58 | - | In Stock | |
| 10 μg | $93 | - | In Stock | |
| 20 μg | $152 | - | In Stock | |
| 50 μg | $298 | 7-10 days | 7-10 days | |
| 100 μg | $577 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:> 90 % as determined by SDS-PAGE
Appearance:Lyophilized powder
Color:White
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first. |
| Description | Ubiquitin-conjugating enzyme E2 D1 (UBE2D1), a member of human E2 ubiquitin-conjugating enzymes, is closely related to SFT, which is short for stimulator of iron (Fe) transport. In other words, UbcH5A is significantly up-regulated in the liver of iron-overloaded patients with hereditary hemochromatosis, as previously published for SFT. Moreover, a complex of UBE2D1 is critical in maintaining KRAS protein stability and propose that targeting such complex may be a unique strategy to degrade mutant KRAS to kill cancer cells. |
| Species | Human |
| Expression System | E. coli |
| Tag | N-His |
| Accession Number | P51668 |
| Construction | A DNA sequence encoding the human UBE2D1 (P51668) (Ala 2-Met 147) was expressed, with a polyhistide tag at the N-terminus. Predicted N terminal: Met |
| Protein Purity | > 90 % as determined by SDS-PAGE |
| Endotoxin | Please contact us for more information. |
| Formulation | Supplied as sterile 25 mM Tris, 100 mM NaCl, 20% glycerol, 0.05% Tween. |
| Reconstitution | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
| Stability & Storage | It is recommended to store the product under sterile conditions at -20°C to -80°C. Samples are stable for up to 12 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| Shipping | Proteins are shipped with blue ice. |
| Synonyms | ubiquitin-conjugating enzyme E2D 1, UBCH5A, UBCH5, UBC4/5, SFT, E2(17)KB1 |
| Research Background |
| Molecular Weight | 18.3 kDa (predicted); 16 kDa (reducing conditions) |
| Storage | Store at low temperature Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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Related Tags: UBE2D1 Protein, Human, Recombinant (His) chemical structure | UBE2D1 Protein, Human, Recombinant (His) molecular weight
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