MFAP3 (Microfibril Associated Protein 3) is a Protein Coding gene. The human gene encoding MFAP3 has a very simple structure, containing only two translated exons encoding a protein of 362 amino acids. The gene was found to be located on chromosome 5q32-q33.2, near the locus 5q21-q31 reported for the fibrillin gene, FBN2, which has been linked to congenital contractural arachnodactyly. MFAP3 is widely expressed in the placenta, urinary bladder, and other tissues. It does not appear to share homology with any other known protein. MFAP3 is a candidate gene for heritable diseases affecting microfibrils. Diseases associated with MFAP3 include Lutembacher's Syndrome and Postural Orthostatic Tachycardia Syndrome.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
100 μg | 5 days | $ 600.00 |
Description | MFAP3 (Microfibril Associated Protein 3) is a Protein Coding gene. The human gene encoding MFAP3 has a very simple structure, containing only two translated exons encoding a protein of 362 amino acids. The gene was found to be located on chromosome 5q32-q33.2, near the locus 5q21-q31 reported for the fibrillin gene, FBN2, which has been linked to congenital contractural arachnodactyly. MFAP3 is widely expressed in the placenta, urinary bladder, and other tissues. It does not appear to share homology with any other known protein. MFAP3 is a candidate gene for heritable diseases affecting microfibrils. Diseases associated with MFAP3 include Lutembacher's Syndrome and Postural Orthostatic Tachycardia Syndrome. |
Species | Human |
Expression System | HEK293 |
Tag | hFc |
Accession Number | P55082-1 |
Synonyms | microfibrillar-associated protein 3 |
Construction | A DNA sequence encoding the human MFAP3 (NP_005918.1) (Met1-Met147) was expressed with the Fc region of human IgG1 at the C-terminus. |
Protein Purity | > 95 % as determined by SDS-PAGE |
Molecular Weight | Approxiamtely 41 kDa |
Endotoxin | < 1.0 EU per μg protein as determined by the LAL method. |
Formulation | Lyophilized from sterile PBS, pH 7.4. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0. 01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA. |
Reconstitution | A hardcopy of datasheet with reconstitution instructions is sent along with the products. Please refer to it for detailed information. |
Stability & Storage |
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Shipping |
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. |
Research Background | MFAP3 (Microfibril Associated Protein 3) is a Protein Coding gene. The human gene encoding MFAP3 has a very simple structure, containing only two translated exons encoding a protein of 362 amino acids. The gene was found to be located on chromosome 5q32-q33.2, near the locus 5q21-q31 reported for the fibrillin gene, FBN2, which has been linked to congenital contractural arachnodactyly. MFAP3 is widely expressed in the placenta, urinary bladder, and other tissues. It does not appear to share homology with any other known protein. MFAP3 is a candidate gene for heritable diseases affecting microfibrils. Diseases associated with MFAP3 include Lutembacher's Syndrome and Postural Orthostatic Tachycardia Syndrome. |
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MFAP3 Protein, Human, Recombinant (hFc) microfibrillar-associated protein 3 recombinant recombinant-proteins proteins protein