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MIT-PZR

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Catalog No. T37656Cas No. 2376848-06-3

MIT-PZR is a mitochondria-targeted fluorescent probe.1It is aggregation-induced emission (AIE) active and displays absorption/emission maxima of 485/705 nm, respectively. MIT-PZR can be used in live cells andin vivo.

MIT-PZR

MIT-PZR

😃Good
Catalog No. T37656Cas No. 2376848-06-3
MIT-PZR is a mitochondria-targeted fluorescent probe.1It is aggregation-induced emission (AIE) active and displays absorption/emission maxima of 485/705 nm, respectively. MIT-PZR can be used in live cells andin vivo.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$42935 days35 days
5 mg$1,53035 days35 days
10 mg$2,58035 days35 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Product Introduction

Bioactivity
Description
MIT-PZR is a mitochondria-targeted fluorescent probe.1It is aggregation-induced emission (AIE) active and displays absorption/emission maxima of 485/705 nm, respectively. MIT-PZR can be used in live cells andin vivo.
Chemical Properties
Molecular Weight562.75
FormulaC33H30N4OS2
Cas No.2376848-06-3
Smiles[#6]-[#6]-[#6]-[#6]-[#6](-[#6]-[#6])-[#6]-[#7]-1-c2ccccc2-[#16]-c2cc(-[#6]=c3s\c(=[#6](\C#N)C#N)n(-c4ccccc4)c3=O)ccc-12 |w:19.19|
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 30 mg/mL (53.31 mM), Sonication is recommended.
DMF: 30 mg/mL (53.31 mM), Sonication is recommended.
Solution Preparation Table
DMSO/DMF
1mg5mg10mg50mg
1 mM1.7770 mL8.8849 mL17.7699 mL88.8494 mL
5 mM0.3554 mL1.7770 mL3.5540 mL17.7699 mL
10 mM0.1777 mL0.8885 mL1.7770 mL8.8849 mL
20 mM0.0888 mL0.4442 mL0.8885 mL4.4425 mL
50 mM0.0355 mL0.1777 mL0.3554 mL1.7770 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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