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Anti-Laminin 5 Polyclonal Antibody (Synonyms: Nicein subunit alpha, LOCS, LAMNA, Laminin-7 subunit alpha, La...)
Catalog No. TMAB-01043 Copy Product Info
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Anti-Laminin 5 Polyclonal Antibody is a Rabbit antibody targeting Laminin 5. Anti-Laminin 5 Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P.
Anti-Laminin 5 Polyclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAB-01043
Synonyms Nicein subunit alpha, LOCS, LAMNA, Laminin-7 subunit alpha, Laminin-6 subunit alpha, Laminin-5 subunit alpha, Laminin5 alpha3, laminin5 alpha 3, Laminin subunit alpha-3, laminin alpha3, laminin alpha 3, Laminin A3, Laminin 5 alpha3, LAMA3A, LAMA3, Kalinin subunit alpha, Epiligrin subunit alpha, Epiligrin 170 kDa subunit, E170
Anti-Laminin 5 Polyclonal Antibody is a Rabbit antibody targeting Laminin 5. Anti-Laminin 5 Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P.
Anti-Laminin 5 Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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| Description | Anti-Laminin 5 Polyclonal Antibody is a Rabbit antibody targeting Laminin 5. Anti-Laminin 5 Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P. |
| Synonyms | Nicein subunit alpha, LOCS, LAMNA, Laminin-7 subunit alpha, Laminin-6 subunit alpha, Laminin-5 subunit alpha, Laminin5 alpha3, laminin5 alpha 3, Laminin subunit alpha-3, laminin alpha3, laminin alpha 3, Laminin A3, Laminin 5 alpha3, LAMA3A, LAMA3, Kalinin subunit alpha, Epiligrin subunit alpha, Epiligrin 170 kDa subunit, E170 |
| Ig Type | IgG |
| Reactivity | Mouse (predicted:Human,Rat,Dog,Pig,Cow,Horse,Rabbit) |
| Verified Activity | Tissue/cell: mouse stomach wall; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer (0.01M, pH6.0), Boiling bathing for 15 min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30 min; Blocking buffer (normal goat serum) at 37°C for 20 min; Incubation: Anti-Laminin 5 Polyclonal Antibody, Unconjugated (TMAB-01043) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody and DAb staining.  |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Secreted, extracellular space, extracellular matrix, basement membrane. Note=Major component. |
| Tissue Specificity | Skin; respiratory, urinary, and digestive epithelia and in other specialized tissues with prominent secretory or protective functions. Epithelial basement membrane, and epithelial cell tongue that migrates into a wound bed. A differential and focal expres |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | Laminins are basement membrane components thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Laminin 5 is an isoform composed of three distinct subunits, alpha 3, beta 3 and gamma 2, which are bound to each other in a cross-shaped molecule by disulphide bonds. It is a complex glycoprotein thought to be involved in cell adhesion via integrin alpha-3/beta-1 in focal adhesion and integrin alpha-6/beta-4 in hemidesmosomes. It is also involved in signal transduction via tyrosine phosphorylation of pp125-FAK and p80, and differentiation of keratinocytes. The laminin alpha 3 subunit is also thought to be a component of laminin 6 and laminin 7 |
| Immunogen | KLH conjugated synthetic peptide: human LAMA3 |
| Antigen Species | Human |
| Gene Name | LAMA3 |
| Gene ID | |
| Protein Name | Laminin subunit alpha-3 |
| Uniprot ID | |
| Biology Area | Extracellular matrix,Extracellular Matrix,Intermediate Filaments,ECM Proteins,Basal Lamina |
| Function | Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Laminin-5 is thought to be involved in (1) cell adhesion via integrin alpha-3/beta-1 in focal adhesion and integrin alpha-6/beta-4 in hemidesmosomes, (2) signal transduction via tyrosine phosphorylation of pp125-FAK and p80, (3) differentiation of keratinocytes. |
| Molecular Weight | Theoretical: 367 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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