Home Tools
Log in
Cart

CD19 Protein, Human, Recombinant (hFc)

Catalog No. TMPY-05427
Synonyms: CVID3, B4, CD19 molecule

CD19 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 56.8 kDa and the accession number is P15391-2.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
CD19 Protein, Human, Recombinant (hFc)
Pack Size Availability Price/USD Quantity
50 μg In stock $ 255.00
100 μg 5 days $ 435.00
200 μg 5 days $ 741.00
500 μg 5 days $ 1,490.00
Bulk Inquiry
Get quote
Select Batch  
Contact us for more batch information
Biological Description
Technical Params
Product Properties
References and Literature
Biological Information Testing in progress
Description CD19 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 56.8 kDa and the accession number is P15391-2.
Species Human
Expression System HEK293 Cells
Tag C-hFc
Accession Number P15391-2
Synonyms CVID3, B4, CD19 molecule
Construction The Human CD19 (NP_001171569.1) (Met1-Lys291) was expressed with the Fc region of Human IgG1 at the C-terminus.
Protein Purity > 95 % as determined by SDS-PAGE.

Molecular Weight 56.8 kDa (predicted)
Endotoxin < 1.0 EU/μg of the protein as determined by the LAL method.
Formulation Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Stability & Storage

It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

Shipping

In general, Lyophilized powders are shipping with blue ice.

Research Background The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. Cluster of differentiation 19 (CD19) is a member of CD system. CD19 is a cell surface molecule that assembles with the antigen receptor of B-cells. This results in a descent in the threshold for antigen receptor-dependent stimulation. A simplified view holds that the ability of B-cells to respond to the various antigens in a specific and sensitive manner is achieved in the presence of low-affinity antigen receptors. CD19 primarily acts as a B-cell co-receptor in conjunction with CD21 and CD81. The formation of the receptor complex is induced by antigen and CD19, induced by exogenous antigen, has been found cytoplasmic tail phosphorylated and bind to sIg.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy

References and Literature

Calculator

Reconstitution Calculator
Recombinant Proteins Dilute Calculator
Specific Activity Calculator
=
÷
X
=
X
(Unit/mg)
= 106 ÷
ng/mL

bottom

Tech Support

Please read the User Guide of Recombinant Proteins for more specific information.

Keywords

CD19 Protein, Human, Recombinant (hFc) B-4 B 4 CVID-3 CVID3 B4 CD19 molecule CVID 3 recombinant recombinant-proteins proteins protein

 

TargetMol