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Anti-Selenoprotein W Polyclonal Antibody (Synonyms: SEPW1, SELW_RAT, SELW, Selenoprotein W, MGC105482)
Catalog No. TMAB-01672 Copy Product Info
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Anti-Selenoprotein W Polyclonal Antibody is a Rabbit antibody targeting Selenoprotein W. Anti-Selenoprotein W Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P.
Anti-Selenoprotein W Polyclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAB-01672
Synonyms SEPW1, SELW_RAT, SELW, Selenoprotein W, MGC105482
Anti-Selenoprotein W Polyclonal Antibody is a Rabbit antibody targeting Selenoprotein W. Anti-Selenoprotein W Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P.
Anti-Selenoprotein W Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
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| Description | Anti-Selenoprotein W Polyclonal Antibody is a Rabbit antibody targeting Selenoprotein W. Anti-Selenoprotein W Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P. |
| Synonyms | SEPW1, SELW_RAT, SELW, Selenoprotein W, MGC105482 |
| Ig Type | IgG |
| Reactivity | Rat (predicted:Human,Mouse,Sheep) |
| Verified Activity | Paraformaldehyde-fixed, paraffin embedded (Rat heart); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 min; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (Selenoprotein W) Polyclonal Antibody, Unconjugated (TMAB-01672) at 1:500 overnight at 4°C, followed by a conjugated secondary for 20 min and DAB staining.  |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm. |
| Tissue Specificity | Ubiquitously expressed with highest levels in skeletal muscle and heart, moderate levels in brain, spinal cord, thyroid, spleen, prostate, ovary, small intestine and colon, and lowest levels in liver and lymph node. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | This gene encodes a selenoprotein containing a selenocysteine (Sec) residue, which is encoded by the UGA codon that normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, the Sec insertion sequence (SECIS) element that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. This protein is highly expressed in skeletal muscle and brain. It belongs to the SelWTH family, which possesses a thioredoxin-like fold and a conserved CxxU (C is cysteine, U is Sec) motif, suggesting a redox function for this gene. Studies in mouse show that this selenoprotein is involved in muscle growth and differentiation, and in the protection of neurons from oxidative stress during neuronal development. A pseudogene for this locus has been identified on chromosome 10. [provided by RefSeq, May 2017]. |
| Immunogen | KLH conjugated synthetic peptide: mouse Selenoprotein W |
| Antigen Species | Mouse |
| Gene Name | SELENOW |
| Protein Name | Selenoprotein W |
| Function | Plays a role as a glutathione (GSH)-dependent antioxidant. May be involved in a redox-related process. May play a role in the myopathies of selenium deficiency. |
| Molecular Weight | Theoretical: 9.5 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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