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Anti-RIPK1 Antibody (1B304)

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Catalog No. TMAC-03610

Anti-RIPK1 Antibody (1B304) is a Rabbit antibody targeting RIPK1. Anti-RIPK1 Antibody (1B304) can be used in WB,FCM.

Anti-RIPK1 Antibody (1B304)

Anti-RIPK1 Antibody (1B304)

😃Good
Catalog No. TMAC-03610
Anti-RIPK1 Antibody (1B304) is a Rabbit antibody targeting RIPK1. Anti-RIPK1 Antibody (1B304) can be used in WB,FCM.
Pack SizePriceAvailabilityQuantity
50 μL$2987-10 days
100 μL$4977-10 days
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Product Introduction

Bioactivity
Description
Anti-RIPK1 Antibody (1B304) is a Rabbit antibody targeting RIPK1. Anti-RIPK1 Antibody (1B304) can be used in WB,FCM.
Ig Type
IgG
Reactivity
Human
Application
Recommended Dose
WB: 1:1000-5000; FCM: 1:50-100
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundIn contrast to growth factors which promote cell proliferation, FAS ligand (FAS-L) and the tumor necrosis factors (TNFs) rapidly induce apoptosis. Cellular response to FAS-L and TNF is mediated by structurally related receptors containing a conserved "death domain" and belonging to the TNF receptor superfamily. TRADD, FADD and RIP are FAS/TNF-R1 interacting proteins that contain a death domain homologous region (DDH). TRADD (TNF-R1-associated death domain) and FADD (FAS-associated death domain) associate with the death domains of both FAS and TNF-R1 via their DDH regions. Overexpression of TRADD leads to NFkB activation and apoptosis in the absence of TNF. Overexpression of FADD causes apoptosis, which can be blocked by the cow pox protein CrmA, suggesting that FADD lies upstream of ICE and possibly other serine proteases. The receptor interacting protein, RIP, associates with FAS exclusively via its DDH and this association is abrogated in lpr mutants. Unlike TRADD and FADD, RIP contains a putative amino terminal kinase domain.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Antigen Species
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 76 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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