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Anti-SIAE Antibody (6X555)

😃Good
Catalog No. TMAY-02558
Alias YSG2, sialic acid acetylesterase, LSE, CSE-C, CSEC, AIS6

Anti-SIAE Antibody (6X555) is a Mouse antibody targeting SIAE. Anti-SIAE Antibody (6X555) can be used in IHC-P.

Anti-SIAE Antibody (6X555)

Anti-SIAE Antibody (6X555)

😃Good
Catalog No. TMAY-02558Alias YSG2, sialic acid acetylesterase, LSE, CSE-C, CSEC, AIS6
Anti-SIAE Antibody (6X555) is a Mouse antibody targeting SIAE. Anti-SIAE Antibody (6X555) can be used in IHC-P.
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100 μL$198 7-10 days
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Product Introduction

Bioactivity
Description
Anti-SIAE Antibody (6X555) is a Mouse antibody targeting SIAE. Anti-SIAE Antibody (6X555) can be used in IHC-P.
AliasYSG2, sialic acid acetylesterase, LSE, CSE-C, CSEC, AIS6
Ig Type
Monoclonal Mouse IgG1
Clone
6X555
Reactivity
Human
Verified Activity
1. Immunochemical staining of human SIAE in human prostate with mouse monoclonal antibody (1:60, formalin-fixed paraffin embedded sections).

2. Immunochemical staining of human SIAE in human colon carcinoma with mouse monoclonal antibody (1:60, formalin-fixed paraffin embedded sections).
Application
IHC-P
Recommended Dose
IHC-P: 1:50-1:200
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human SIAE/sialate O-acetylesterase (rh SIAE/sialate O-acetylesterase; TMPY-02952; Q9HAT2-1; Met1-Lys523). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundSialate O-acetylesterase belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. It is widely expressed with high expression in the testis, prostate, and colon. The systematic name of this enzyme class is N-acyl-O-acetylneuraminate O-acetylhydrolase. Other names in common use include N-acetylneuraminate acetyltransferase, sialate 9(4)-O-acetylesterase, and sialidase. Sialate O-acetylesterase catalyzes the removal of O-acetyl ester groups from position 9 of the parent sialic acid, N-acetylneuraminic acid. Defects in Sialate O-acetylesterase are a cause of autoimmune disease type 6 (AIS6). Individuals manifesting susceptibility to autoimmune disease type 6 can suffer from juvenile idiopathic arthritis, rheumatoid arthritis, multiple sclerosis, Sjogren syndrome, systemic lupus erythematosus, type 1 diabetes, ulcerative colitis, and Crohn disease.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Human SIAE/sialate O-acetylesterase Protein (TMPY-02952)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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