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Anti-SIAE Antibody (6X555)
😃Good
Catalog No. TMAY-02558
Alias YSG2, sialic acid acetylesterase, LSE, CSE-C, CSEC, AIS6
Anti-SIAE Antibody (6X555) is a Mouse antibody targeting SIAE. Anti-SIAE Antibody (6X555) can be used in IHC-P.
Anti-SIAE Antibody (6X555)
Anti-SIAE Antibody (6X555)
😃Good
Catalog No. TMAY-02558Alias YSG2, sialic acid acetylesterase, LSE, CSE-C, CSEC, AIS6
Anti-SIAE Antibody (6X555) is a Mouse antibody targeting SIAE. Anti-SIAE Antibody (6X555) can be used in IHC-P.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $198 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Mouse Monoclonal Application: IHC-P Reactivity: Human |
| Alias | YSG2, sialic acid acetylesterase, LSE, CSE-C, CSEC, AIS6 |
| Ig Type | Mouse IgG1 |
| Clone | 6X555 |
| Reactivity | Human |
| Verified Activity | 1. Immunochemical staining of human SIAE in human prostate with mouse monoclonal antibody (1:60, formalin-fixed paraffin embedded sections). 2. Immunochemical staining of human SIAE in human colon carcinoma with mouse monoclonal antibody (1:60, formalin-fixed paraffin embedded sections). |
| Application | IHC-P |
| Recommended Dose | IHC-P: 1:50-1:200 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human SIAE/sialate O-acetylesterase (rh SIAE/sialate O-acetylesterase; TMPY-02952; Q9HAT2-1; Met1-Lys523). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Sialate O-acetylesterase belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. It is widely expressed with high expression in the testis, prostate, and colon. The systematic name of this enzyme class is N-acyl-O-acetylneuraminate O-acetylhydrolase. Other names in common use include N-acetylneuraminate acetyltransferase, sialate 9(4)-O-acetylesterase, and sialidase. Sialate O-acetylesterase catalyzes the removal of O-acetyl ester groups from position 9 of the parent sialic acid, N-acetylneuraminic acid. Defects in Sialate O-acetylesterase are a cause of autoimmune disease type 6 (AIS6). Individuals manifesting susceptibility to autoimmune disease type 6 can suffer from juvenile idiopathic arthritis, rheumatoid arthritis, multiple sclerosis, Sjogren syndrome, systemic lupus erythematosus, type 1 diabetes, ulcerative colitis, and Crohn disease. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human SIAE/sialate O-acetylesterase Protein (TMPY-02952) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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