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GPCR agonist-2

Name: GPCR agonist-2
Brand: TargetMol
SKU: T60074
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T60074Cas No. 291528-35-3

Alias 4-(Cyclopropylamino)-3-nitrobenzoic acid

GPCR agonist-2 (4-(Cyclopropylamino)-3-nitrobenzoic acid) is an agonist of the orphan human GPCR GPR109B.

GPCR agonist-2

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Purity: 99.96%

Catalog No. T60074Alias 4-(Cyclopropylamino)-3-nitrobenzoic acidCas No. 291528-35-3

GPCR agonist-2 (4-(Cyclopropylamino)-3-nitrobenzoic acid) is an agonist of the orphan human GPCR GPR109B.

Pack Size	Price	USA Warehouse	Global Warehouse
10 mg	$30	-	In Stock
25 mg	$41	-	In Stock
50 mg	$56	-	In Stock
1 mL x 10 mM (in DMSO)	$29	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Batch Information

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Purity:99.96%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	GPCR agonist-2 (4-(Cyclopropylamino)-3-nitrobenzoic acid) is an agonist of the orphan human GPCR GPR109B.
Synonyms	4-(Cyclopropylamino)-3-nitrobenzoic acid

Chemical Properties

Molecular Weight	222.2
Formula	C₁₀H₁₀N₂O₄
Cas No.	291528-35-3
Smiles	N(=O)(=O)C1=C(NC2CC2)C=CC(C(O)=O)=C1

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (225.02 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.5005 mL	22.5023 mL	45.0045 mL	225.0225 mL
5 mM	0.9001 mL	4.5005 mL	9.0009 mL	45.0045 mL
10 mM	0.4500 mL	2.2502 mL	4.5005 mL	22.5023 mL
20 mM	0.2250 mL	1.1251 mL	2.2502 mL	11.2511 mL
50 mM	0.0900 mL	0.4500 mL	0.9001 mL	4.5005 mL
100 mM	0.0450 mL	0.2250 mL	0.4500 mL	2.2502 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc